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Summary of Significant Accounting Policies - Addtional Information (Detail) - USD ($)
12 Months Ended
Dec. 31, 2017
Dec. 31, 2016
Dec. 31, 2015
Significant Accounting Policies [Line Items]      
Other Intangible Assets, Net   $ 900,000  
Other Finite-Lived Intangible Assets, Gross   2,500,000  
Cash $ 5,965,000 9,375,000 $ 8,854,000
Depreciation 251,000 43,000  
Research and Development Costs Expenses 5,500,000 5,500,000  
Amortization $ 160,000 $ 161,000  
Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount 562,041 544,167  
Net Income Loss $ (7,023,000) $ (6,750,000)  
Retained Earnings (Accumulated Deficit), Total $ (39,157,000) $ (32,134,000)  
Warrant      
Significant Accounting Policies [Line Items]      
Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount 1,277,784 595,118  
Furniture and fixtures      
Significant Accounting Policies [Line Items]      
Property, Plant and Equipment, Useful Life 7 years    
Computers and equipment      
Significant Accounting Policies [Line Items]      
Property, Plant and Equipment, Useful Life 3 years    
Scientific equipment      
Significant Accounting Policies [Line Items]      
Property, Plant and Equipment, Useful Life 7 years    
Leasehold improvements      
Significant Accounting Policies [Line Items]      
Property, Plant and Equipment, Estimated Useful Lives Lesser of useful life or lease term    
Preclinical Stage Biotechnology Company      
Significant Accounting Policies [Line Items]      
Development Project Service Evaluation Exchange Cost $ 50,000    
Technology Services Revenue 50,000    
Jp Morgan Chase Bank      
Significant Accounting Policies [Line Items]      
Cash, FDIC Insured Amount 5,700,000 $ 9,100,000  
Federal Deposit Insurance 250,000    
Cash   9,400,000  
Md Anderson      
Significant Accounting Policies [Line Items]      
Other Intangible Assets, Net 800,000    
Other Finite-Lived Intangible Assets, Gross 2,500,000    
Amortization of Intangible Assets 1,700,000    
Technology Amortization Annually $ 200,000 $ 200,000