EXHIBIT 23.1

CONSENT OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM

     We consent to the incorporation by reference in the Registration Statement on Form S-8 (No. 333-128805) pertaining to the 2005 Stock Incentive Plan and 2001 Stock Incentive Plan of Genomic Health, Inc., the Registration Statement on Form S-8 (No. 333-163006) pertaining to the 2005 Stock Incentive Plan of Genomic Health, Inc., and the Registration Statement on Form S-3 (No. 333-167868) of Genomic Health, Inc. of our reports dated March 11, 2011, with respect to the consolidated financial statements and schedule of Genomic Health, Inc., and the effectiveness of internal control over financial reporting of Genomic Health, Inc., included in this Annual Report (Form 10-K) for the year ended December 31, 2010.

/s/ Ernst & Young LLP

Palo Alto, California
March 11, 2011