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Stock-Based Compensation (Tables)
6 Months Ended
Jun. 30, 2022
Stock-based compensation  
Schedule of stock-based compensation expense

Three Months Ended June 30, 

Six Months Ended June 30, 

    

2022

    

2021

    

2022

    

2021

    

General and administrative

$

72,000

$

43,000

$

259,000

$

99,000

Research and development

169,000

17,000

278,000

26,000

$

241,000

$

60,000

$

537,000

$

125,000

Schedule of stock option activity

    

Options Outstanding

Weighted

Weighted-

Average

Average

Remaining

Aggregate

Number

Exercise

Contractual

Intrinsic

    

    

of Shares

    

Price

    

Term (in years)

    

Value

Balance, December 31, 2021

 

452,999

$

20.71

 

9.42

$

Authorized

Granted

 

491,825

$

1.75

9.66

 

Exercised

 

$

$

Forfeitures/adjustments

 

(94,271)

$

3.37

 

Balance, June 30, 2022

 

850,553

$

11.67

 

9.26

$

Exercisable at June 30, 2022

 

40,302

$

179.88

 

6.51

$

Stock options  
Stock-based compensation  
Schedule of weighted-average assumptions used for estimating the fair value of the stock compensation granted

Six months ended June 30, 

    

2022

    

2021

 

    

Risk-free interest rate

 

2.01

%  

1.02

%  

 

Expected volatility

 

121.49

%  

123.32

%  

 

Expected term

 

5.85

years  

6.25

years

 

Expected dividend yield

 

0

%  

0

%  

 

Weighted average grant date fair value

$

1.51

$

0.25

SAR awards  
Stock-based compensation  
Schedule of weighted-average assumptions used for estimating the fair value of the stock compensation granted

    

As of June 30, 2022

    

Risk-free interest rate

 

3.01

%  

Expected volatility

 

133.44

%  

Expected term

 

5.14

years  

Expected dividend yield

 

0

%