The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
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COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
360 DIGITECH INC ADR USD.00001 88557W101 312 12,000 SH   SOLE   12,000 0 0
3M CO COMMON STOCK USD.01 88579Y101 2,066 10,720 SH   SOLE   10,720 0 0
5 01 ACQUISITION CORP CL A COMMON STOCK USD.0001 33836P105 748 75,000 SH   SOLE   75,000 0 0
890 5TH AVENUE PARTNERS CL A COMMON STOCK USD.0001 28250A105 969 99,996 SH   SOLE   99,996 0 0
890 5TH AVENUE PARTNERS CL A 890 5TH AVENUE PA CL A CW27 28250A113 27 33,332 SH   SOLE   33,332 0 0
890 5TH AVENUE PARTNERS INC UNIT USD.0001 28250A204 0 4 SH   SOLE   4 0 0
A10 NETWORKS INC COMMON STOCK USD.00001 002121101 521 54,181 SH   SOLE   54,181 0 0
ABBOTT LABORATORIES COMMON STOCK 002824100 16,159 134,837 SH   SOLE   134,837 0 0
ABBVIE INC COMMON STOCK USD.01 00287Y109 6,122 56,569 SH   SOLE   56,569 0 0
ABERCROMBIE FITCH CO CL A COMMON STOCK USD.01 002896207 565 16,464 SH   SOLE   16,464 0 0
ABG ACQUISITION CORP I A COMMON STOCK USD.0001 G00496102 768 77,685 SH   SOLE   77,685 0 0
ABIOMED INC COMMON STOCK USD.01 003654100 366 1,147 SH   SOLE   1,147 0 0
ACADIA PHARMACEUTICALS INC COMMON STOCK USD.0001 004225108 82 3,188 SH   SOLE   3,188 0 0
ACCELERATE ACQUISITION CORP UNIT USD.0001 00439D201 1,986 200,000 SH   SOLE   200,000 0 0
ACCENTURE PLC CL A COMMON STOCK USD.0000225 G1151C101 10,333 37,403 SH   SOLE   37,403 0 0
ACCURAY INC COMMON STOCK USD.001 004397105 350 70,762 SH   SOLE   70,762 0 0
ACE CONVERGENCE ACQU CLASS A ACE CONVERGENCE ACQU C CW27 G0083D104 50 25,000 SH   SOLE   25,000 0 0
ACE CONVERGENCE ACQU CLASS A COMMON STOCK USD.0001 G0083D120 499 50,000 SH   SOLE   50,000 0 0
ACI WORLDWIDE INC COMMON STOCK USD.005 004498101 582 15,307 SH   SOLE   15,307 0 0
ACIES ACQUISITION CORP UNIT USD.0001 G0103T121 0 1 SH   SOLE   1 0 0
ACIES ACQUISITION CORP CL A COMMON STOCK USD.0001 G0103T105 995 99,999 SH   SOLE   99,999 0 0
ACIES ACQUISITION CORP CL A ACIES ACQUISITION CL A CW27 G0103T113 51 33,333 SH   SOLE   33,333 0 0
ACTIVISION BLIZZARD INC COMMON STOCK USD.000001 00507V109 1,947 20,934 SH   SOLE   20,934 0 0
ACUITY BRANDS INC COMMON STOCK USD.01 00508Y102 3,808 23,081 SH   SOLE   23,081 0 0
ADIENT PLC COMMON STOCK USD.001 G0084W101 273 6,182 SH   SOLE   6,182 0 0
ADIT EDTECH ACQUISITION COMMON STOCK USD.0001 007024102 241 25,000 SH   SOLE   25,000 0 0
ADIT EDTECH ACQUISITION ADIT EDTECH ACQ CW27 007024110 6 12,500 SH   SOLE   12,500 0 0
ADOBE INC COMMON STOCK USD.0001 00724F101 11,810 24,843 SH   SOLE   24,843 0 0
ADTRAN INC COMMON STOCK USD.01 00738A106 247 14,797 SH   SOLE   14,797 0 0
ADVANCE AUTO PARTS INC COMMON STOCK USD.0001 00751Y106 1,544 8,414 SH   SOLE   8,414 0 0
ADVANCED ENERGY INDUSTRIES COMMON STOCK USD.001 007973100 371 3,397 SH   SOLE   3,397 0 0
ADVANCED MERGER PARTNERS INC UNIT USD.0001 00777J208 50 5,000 SH   SOLE   5,000 0 0
ADVANCED MICRO DEVICES COMMON STOCK USD.01 007903107 878 11,181 SH   SOLE   11,181 0 0
AEA BRIDGES IMPACT CORP CL A COMMON STOCK USD.0001 G01046104 982 100,000 SH   SOLE   100,000 0 0
AEA BRIDGES IMPACT CORP CL A AEA BRIDGES IMPACT COR CW25 G01046112 45 50,000 SH   SOLE   50,000 0 0
AERCAP HOLDINGS NV COMMON STOCK EUR.01 N00985106 235 4,000 SH   SOLE   4,000 0 0
AES CORP COMMON STOCK USD.01 00130H105 791 29,496 SH   SOLE   29,496 0 0
AEVA TECHNOLOGIES INC COMMON STOCK USD.0001 00835Q103 0 2 SH   SOLE   2 0 0
AEVA TECHNOLOGIES INC INTERPRIVATE ACQUISITI CW24 00835Q111 0 2 SH   SOLE   2 0 0
AF ACQUISITION CORP UNIT USD.0001 001040203 493 50,000 SH   SOLE   50,000 0 0
AFFILIATED MANAGERS GROUP COMMON STOCK USD.01 008252108 188 1,259 SH   SOLE   1,259 0 0
AFLAC INC COMMON STOCK USD.1 001055102 4,356 85,117 SH   SOLE   85,117 0 0
AFRICAN GOLD ACQUISITION COR UNIT USD.0001 G0112R116 99 10,000 SH   SOLE   10,000 0 0
AGCO CORP COMMON STOCK USD.01 001084102 2,552 17,763 SH   SOLE   17,763 0 0
AGILE GROWTH CORP UNIT USD.0001 G01202129 992 100,000 SH   SOLE   100,000 0 0
AGILENT TECHNOLOGIES INC COMMON STOCK USD.01 00846U101 9,645 75,858 SH   SOLE   75,858 0 0
AGILYSYS INC COMMON STOCK USD.3 00847J105 518 10,807 SH   SOLE   10,807 0 0
AJAX I CL A AJAX I CL A CW26 G0190X126 68 40,000 SH   SOLE   40,000 0 0
AKAMAI TECHNOLOGIES INC COMMON STOCK USD.01 00971T101 251 2,462 SH   SOLE   2,462 0 0
AKEBIA THERAPEUTICS INC COMMON STOCK USD.0001 00972D105 245 72,469 SH   SOLE   72,469 0 0
ALARM.COM HOLDINGS INC COMMON STOCK 011642105 503 5,822 SH   SOLE   5,822 0 0
ALBANY INTL CORP CL A COMMON STOCK USD.001 012348108 740 8,871 SH   SOLE   8,871 0 0
ALBEMARLE CORP COMMON STOCK USD.01 012653101 403 2,755 SH   SOLE   2,755 0 0
ALBIREO PHARMA INC COMMON STOCK USD.01 01345P106 229 6,488 SH   SOLE   6,488 0 0
ALCOA CORP COMMON STOCK USD.01 013872106 4,775 146,966 SH   SOLE   146,966 0 0
ALEXANDRIA REAL ESTATE EQUIT REIT USD.01 015271109 3,515 21,395 SH   SOLE   21,395 0 0
ALEXION PHARMACEUTICALS INC COMMON STOCK USD.0001 015351109 4,413 28,862 SH   SOLE   28,862 0 0
ALIBABA GROUP HOLDING SP ADR ADR USD.000025 01609W102 44,678 197,055 SH   SOLE   197,055 0 0
ALIGN TECHNOLOGY INC COMMON STOCK USD.0001 016255101 1,577 2,913 SH   SOLE   2,913 0 0
ALKURI GLOBAL ACQUISITION CO UNIT USD.0001 66981N202 741 75,000 SH   SOLE   75,000 0 0
ALLEGHANY CORP COMMON STOCK USD1.0 017175100 507 810 SH   SOLE   810 0 0
ALLEGHENY TECHNOLOGIES INC COMMON STOCK USD.1 01741R102 651 30,931 SH   SOLE   30,931 0 0
ALLEGION PLC COMMON STOCK USD.01 G0176J109 200 1,593 SH   SOLE   1,593 0 0
ALLEGRO MICROSYSTEMS INC COMMON STOCK USD.01 01749D105 319 12,603 SH   SOLE   12,603 0 0
ALLIANT ENERGY CORP COMMON STOCK USD.01 018802108 142 2,622 SH   SOLE   2,622 0 0
ALLISON TRANSMISSION HOLDING COMMON STOCK USD.01 01973R101 4,725 115,712 SH   SOLE   115,712 0 0
ALLSTATE CORP COMMON STOCK USD.01 020002101 4,244 36,935 SH   SOLE   36,935 0 0
ALLY FINANCIAL INC COMMON STOCK USD.1 02005N100 826 18,267 SH   SOLE   18,267 0 0
ALPHA CAPITAL ACQUISITION CO UNIT USD.0001 G0316P114 995 100,000 SH   SOLE   100,000 0 0
ALPHABET INC CL A COMMON STOCK USD.001 02079K305 19,099 9,260 SH   SOLE   9,260 0 0
ALPHABET INC CL C COMMON STOCK USD.001 02079K107 78,486 37,941 SH   SOLE   37,941 0 0
ALTIMAR ACQUISITION CORP UNIT USD.0001 G03707125 0 4 SH   SOLE   4 0 0
ALTIMAR ACQUISITION CORP A COMMON STOCK USD.0001 G03707109 988 99,996 SH   SOLE   99,996 0 0
ALTIMAR ACQUISITION CORP A ALTIMAR ACQUISITION CW G03707117 47 33,332 SH   SOLE   33,332 0 0
ALTIMAR ACQUISITION CORP II UNIT USD.0001 G03709113 10 1,000 SH   SOLE   1,000 0 0
ALTIMAR ACQUISITION CORP III UNIT USD.0001 G0370U124 250 25,000 SH   SOLE   25,000 0 0
ALTIMETER GROWTH CORP 2 A COMMON STOCK USD.0001 G0371B109 52 5,000 SH   SOLE   5,000 0 0
ALTIMETER GROWTH CORP CL A COMMON STOCK USD.0001 G0370L108 176 15,000 SH   SOLE   15,000 0 0
ALTIMETER GROWTH CORP CL A ALTIMETER GROWTH CORP CW25 G0370L116 9 3,000 SH   SOLE   3,000 0 0
ALTRIA GROUP INC COMMON STOCK USD.333 02209S103 1,392 27,211 SH   SOLE   27,211 0 0
AMAZON.COM INC COMMON STOCK USD.01 023135106 105,712 34,166 SH   SOLE   34,166 0 0
AMC NETWORKS INC A COMMON STOCK 00164V103 823 15,478 SH   SOLE   15,478 0 0
AMCOR PLC COMMON STOCK USD.01 G0250X107 314 26,898 SH   SOLE   26,898 0 0
AMDOCS LTD COMMON STOCK GBP.0001 G02602103 1,674 23,857 SH   SOLE   23,857 0 0
AMERCO COMMON STOCK USD.25 023586100 315 515 SH   SOLE   515 0 0
AMEREN CORPORATION COMMON STOCK USD.01 023608102 361 4,439 SH   SOLE   4,439 0 0
AMERICAN AIRLINES GROUP INC COMMON STOCK 02376R102 3,257 136,274 SH   SOLE   136,274 0 0
AMERICAN ASSETS TRUST INC REIT USD.01 024013104 481 14,837 SH   SOLE   14,837 0 0
AMERICAN CAMPUS COMMUNITIES REIT USD.01 024835100 284 6,581 SH   SOLE   6,581 0 0
AMERICAN EAGLE OUTFITTERS COMMON STOCK USD.01 02553E106 675 23,072 SH   SOLE   23,072 0 0
AMERICAN ELECTRIC POWER COMMON STOCK USD6.5 025537101 753 8,889 SH   SOLE   8,889 0 0
AMERICAN HOMES 4 RENT A REIT USD.01 02665T306 2,087 62,592 SH   SOLE   62,592 0 0
AMERICAN INTERNATIONAL GROUP COMMON STOCK USD2.5 026874784 686 14,843 SH   SOLE   14,843 0 0
AMERICAN PUBLIC EDUCATION COMMON STOCK USD.01 02913V103 488 13,697 SH   SOLE   13,697 0 0
AMERICAN STATES WATER CO COMMON STOCK 029899101 451 5,958 SH   SOLE   5,958 0 0
AMERICAN TOWER CORP REIT USD.01 03027X100 6,841 28,618 SH   SOLE   28,618 0 0
AMERICAN WATER WORKS CO INC COMMON STOCK USD.01 030420103 437 2,917 SH   SOLE   2,917 0 0
AMERICOLD REALTY TRUST REIT USD.01 03064D108 1,468 38,162 SH   SOLE   38,162 0 0
AMERIPRISE FINANCIAL INC COMMON STOCK USD.01 03076C106 559 2,403 SH   SOLE   2,403 0 0
AMERIS BANCORP COMMON STOCK USD1.0 03076K108 1,640 31,224 SH   SOLE   31,224 0 0
AMERISOURCEBERGEN CORP COMMON STOCK USD.01 03073E105 298 2,524 SH   SOLE   2,524 0 0
AMETEK INC COMMON STOCK USD.01 031100100 21,180 165,819 SH   SOLE   165,819 0 0
AMGEN INC COMMON STOCK USD.0001 031162100 3,853 15,485 SH   SOLE   15,485 0 0
AMICUS THERAPEUTICS INC COMMON STOCK USD.01 03152W109 642 65,000 SH   SOLE   65,000 0 0
AMKOR TECHNOLOGY INC COMMON STOCK USD.001 031652100 3,940 166,190 SH   SOLE   166,190 0 0
AMN HEALTHCARE SERVICES INC COMMON STOCK USD.01 001744101 1,364 18,508 SH   SOLE   18,508 0 0
AMPHENOL CORP CL A COMMON STOCK USD.001 032095101 10,106 153,195 SH   SOLE   153,195 0 0
AMPLITUDE HEALTHCARE ACQ A COMMON STOCK 03212A105 2,982 300,000 SH   SOLE   300,000 0 0
ANALOG DEVICES INC COMMON STOCK USD.167 032654105 17,930 115,616 SH   SOLE   115,616 0 0
ANGLOGOLD ASHANTI SPON ADR ADR 035128206 330 15,000 SH   SOLE   15,000 0 0
ANSYS INC COMMON STOCK USD.01 03662Q105 1,530 4,507 SH   SOLE   4,507 0 0
ANTARES PHARMA INC COMMON STOCK USD.01 036642106 296 71,970 SH   SOLE   71,970 0 0
ANTERO MIDSTREAM CORP COMMON STOCK 03676B102 188 20,865 SH   SOLE   20,865 0 0
ANTERO RESOURCES CORP COMMON STOCK USD.01 03674X106 307 30,139 SH   SOLE   30,139 0 0
ANTHEM INC COMMON STOCK USD.01 036752103 23,243 64,753 SH   SOLE   64,753 0 0
ANZU SPECIAL ACQUISITION COR UNIT USD.0001 03737A200 2,994 300,000 SH   SOLE   300,000 0 0
APA CORP COMMON STOCK USD.625 03743Q108 712 39,774 SH   SOLE   39,774 0 0
APOLLO STRATEGIC GROWTH CAPI UNIT USD.00025 G0412A110 399 40,000 SH   SOLE   40,000 0 0
APOLLO STRATEGIC GROWTH CL A COMMON STOCK USD.00005 G0411R106 1,485 150,000 SH   SOLE   150,000 0 0
APOLLO STRATEGIC GROWTH CL A APOLLO STRATEGIC GROWT CW27 G0411R114 63 50,000 SH   SOLE   50,000 0 0
APPLE HOSPITALITY REIT INC REIT NPV 03784Y200 1,278 87,718 SH   SOLE   87,718 0 0
APPLE INC COMMON STOCK USD.00001 037833100 123,016 1,007,093 SH   SOLE   1,007,093 0 0
APPLIED INDUSTRIAL TECH INC COMMON STOCK 03820C105 982 10,770 SH   SOLE   10,770 0 0
APPLIED MATERIALS INC COMMON STOCK USD.01 038222105 15,328 114,730 SH   SOLE   114,730 0 0
APTIV PLC COMMON STOCK USD.01 G6095L109 3,990 28,931 SH   SOLE   28,931 0 0
AQUESTIVE THERAPEUTICS INC COMMON STOCK USD.001 03843E104 191 36,752 SH   SOLE   36,752 0 0
ARCHER DANIELS MIDLAND CO COMMON STOCK 039483102 1,584 27,797 SH   SOLE   27,797 0 0
ARCHIMEDES TECH SPAC PARTNER UNIT USD.0001 039562202 742 75,000 SH   SOLE   75,000 0 0
ARCLIGHT CLEAN TRANSITION A ARCLIGHT CLEAN TRANSIT CW27 G04561125 323 56,141 SH   SOLE   56,141 0 0
ARCLIGHT CLEAN TRANSITION II UNIT USD.0001 G0R21B120 250 25,000 SH   SOLE   25,000 0 0
ARCTOS NORTHSTAR ACQUISITION UNIT USD.0001 G0477L118 1,499 150,000 SH   SOLE   150,000 0 0
ARENA PHARMACEUTICALS INC COMMON STOCK USD.0001 040047607 1,406 20,267 SH   SOLE   20,267 0 0
ARES ACQUISITION CORP UNIT USD.0001 G33032114 2,000 200,000 SH   SOLE   200,000 0 0
ARISTA NETWORKS INC COMMON STOCK USD.0001 040413106 294 973 SH   SOLE   973 0 0
ARMADA HOFFLER PROPERTIES IN REIT USD.01 04208T108 1,052 83,915 SH   SOLE   83,915 0 0
ARROW ELECTRONICS INC COMMON STOCK USD1.0 042735100 4,475 40,385 SH   SOLE   40,385 0 0
ARROWHEAD PHARMACEUTICALS IN COMMON STOCK USD.001 04280A100 636 9,592 SH   SOLE   9,592 0 0
ARTHUR J GALLAGHER CO COMMON STOCK USD1.0 363576109 544 4,364 SH   SOLE   4,364 0 0
ARTISAN PARTNERS ASSET MA A COMMON STOCK USD.01 04316A108 465 8,917 SH   SOLE   8,917 0 0
ARTIUS ACQUISITION INC UNIT USD.0001 04316G204 0 2 SH   SOLE   2 0 0
ARTIUS ACQUISITION INC CL A COMMON STOCK USD.0001 04316G105 2,020 199,998 SH   SOLE   199,998 0 0
ARTIUS ACQUISITION INC CL A ARTIUS ACQUISITION INC CW26 04316G113 115 66,666 SH   SOLE   66,666 0 0
ASCENDANT DIGITAL ACQUISIT A COMMON STOCK USD.0001 G05155109 1,485 149,998 SH   SOLE   149,998 0 0
ASCENDANT DIGITAL ACQUISIT A ASCENDANT DIGITAL ACQU CW25 G05155117 76 74,999 SH   SOLE   74,999 0 0
ASCENDANT DIGITAL ACQUISITIO UNIT USD.0001 G05155125 0 2 SH   SOLE   2 0 0
ASML HOLDING NV NY REG SHS NY REG SHRS EUR.09 N07059210 854 1,384 SH   SOLE   1,384 0 0
ASPEN TECHNOLOGY INC COMMON STOCK USD.1 045327103 1,862 12,903 SH   SOLE   12,903 0 0
ASPIRATIONAL CONSUMER LIFE A COMMON STOCK USD.0001 G05436103 251 25,034 SH   SOLE   25,034 0 0
ASPIRATIONAL CONSUMER LIFE A ASPIRATIONAL CONSUMER CW25 G05436111 59 41,666 SH   SOLE   41,666 0 0
ASPIRATIONAL CONSUMER LIFEST UNIT USD.0001 G05436129 0 2 SH   SOLE   2 0 0
ASSOCIATED BANC CORP COMMON STOCK USD.01 045487105 53 2,474 SH   SOLE   2,474 0 0
ASSURANT INC COMMON STOCK USD.01 04621X108 155 1,095 SH   SOLE   1,095 0 0
ATT INC COMMON STOCK USD1.0 00206R102 4,292 141,785 SH   SOLE   141,785 0 0
ATARA BIOTHERAPEUTICS INC COMMON STOCK USD.0001 046513107 178 12,428 SH   SOLE   12,428 0 0
ATHENA TECHNOLOGY ACQUISITIO UNIT USD.0001 04687A208 742 75,000 SH   SOLE   75,000 0 0
ATHENE HOLDING LTD CLASS A COMMON STOCK USD.001 G0684D107 3,427 68,000 SH   SOLE   68,000 0 0
ATHLON ACQUISITION CORP A COMMON STOCK USD.0001 04748A106 241 25,000 SH   SOLE   25,000 0 0
ATHLON ACQUISITION CORP A ATHLON ACQUISITION WTS CW26 04748A114 7 12,500 SH   SOLE   12,500 0 0
ATKORE INC COMMON STOCK USD.01 047649108 1,873 26,045 SH   SOLE   26,045 0 0
ATLANTIC AVENUE ACQUISI CL A COMMON STOCK USD.0001 04906P101 1,163 120,000 SH   SOLE   120,000 0 0
ATLANTIC AVENUE ACQUISI CL A ATLANTIC AVENUE ACQUIS CW27 04906P119 44 60,000 SH   SOLE   60,000 0 0
ATLAS CREST INVESTMENT CORP UNIT USD.0001 049287204 250 25,000 SH   SOLE   25,000 0 0
ATLASSIAN CORP PLC CLASS A COMMON STOCK USD.1 G06242104 358 1,698 SH   SOLE   1,698 0 0
ATMOS ENERGY CORP COMMON STOCK 049560105 224 2,265 SH   SOLE   2,265 0 0
ATRICURE INC COMMON STOCK USD.001 04963C209 763 11,647 SH   SOLE   11,647 0 0
AURORA ACQUISITION CORP UNIT USD.0001 G0698L111 1,294 125,000 SH   SOLE   125,000 0 0
AUSTERLITZ ACQUISITION CORP UNIT USD.0001 G0633D117 1,004 100,000 SH   SOLE   100,000 0 0
AUSTERLITZ ACQUISITION CORP UNIT USD.0001 G0633U119 1,003 100,000 SH   SOLE   100,000 0 0
AUTHENTIC EQUITY ACQUISITI A COMMON STOCK USD.0001 G06607108 242 25,000 SH   SOLE   25,000 0 0
AUTHENTIC EQUITY ACQUISITI A AUTHENTIC EQUITY ACQ CW27 G06607124 8 12,500 SH   SOLE   12,500 0 0
AUTODESK INC COMMON STOCK USD.01 052769106 1,193 4,304 SH   SOLE   4,304 0 0
AUTOHOME INC ADR ADR USD.01 05278C107 3,075 32,964 SH   SOLE   32,964 0 0
AUTOMATIC DATA PROCESSING COMMON STOCK USD.1 053015103 2,178 11,555 SH   SOLE   11,555 0 0
AUTONATION INC COMMON STOCK USD.01 05329W102 3,975 42,643 SH   SOLE   42,643 0 0
AUTOZONE INC COMMON STOCK USD.01 053332102 4,918 3,502 SH   SOLE   3,502 0 0
AVALONBAY COMMUNITIES INC REIT USD.01 053484101 4,681 25,371 SH   SOLE   25,371 0 0
AVANTI ACQUISITION CORP A COMMON STOCK USD.0001 G0682V109 977 100,000 SH   SOLE   100,000 0 0
AVANTI ACQUISITION CORP A AVANTI ACQUISITION A CW25 G0682V125 53 50,000 SH   SOLE   50,000 0 0
AVANTOR INC COMMON STOCK USD.01 05352A100 1,003 34,656 SH   SOLE   34,656 0 0
AVERY DENNISON CORP COMMON STOCK USD1.0 053611109 478 2,601 SH   SOLE   2,601 0 0
AVNET INC COMMON STOCK USD1.0 053807103 50 1,211 SH   SOLE   1,211 0 0
AXONICS INC COMMON STOCK USD.0001 05465P101 919 15,338 SH   SOLE   15,338 0 0
BG FOODS INC COMMON STOCK USD.01 05508R106 243 7,831 SH   SOLE   7,831 0 0
BADGER METER INC COMMON STOCK USD1.0 056525108 711 7,639 SH   SOLE   7,639 0 0
BAKER HUGHES CO COMMON STOCK USD.0001 05722G100 415 19,224 SH   SOLE   19,224 0 0
BANCORPSOUTH BANK COMMON STOCK 05971J102 917 28,225 SH   SOLE   28,225 0 0
BANK OF AMERICA CORP COMMON STOCK USD.01 060505104 40,580 1,048,837 SH   SOLE   1,048,837 0 0
BANK OF N.T. BUTTERFIELDSON COMMON STOCK BMD1.0 G0772R208 614 16,067 SH   SOLE   16,067 0 0
BANK OF NEW YORK MELLON CORP COMMON STOCK USD.01 064058100 1,161 24,544 SH   SOLE   24,544 0 0
BARRICK GOLD CORP COMMON STOCK 067901108 3,166 159,917 SH   SOLE   159,917 0 0
BAXTER INTERNATIONAL INC COMMON STOCK USD1.0 071813109 1,037 12,300 SH   SOLE   12,300 0 0
BECTON DICKINSON AND CO COMMON STOCK USD1.0 075887109 11,340 46,639 SH   SOLE   46,639 0 0
BED BATH BEYOND INC COMMON STOCK USD.01 075896100 274 9,384 SH   SOLE   9,384 0 0
BEIGENE LTD ADR ADR USD.0001 07725L102 502 1,442 SH   SOLE   1,442 0 0
BERKSHIRE HATHAWAY INC CL B COMMON STOCK USD.0033 084670702 32,450 127,022 SH   SOLE   127,022 0 0
BERKSHIRE HILLS BANCORP INC COMMON STOCK USD.01 084680107 426 19,099 SH   SOLE   19,099 0 0
BEST BUY CO INC COMMON STOCK USD.1 086516101 1,382 12,040 SH   SOLE   12,040 0 0
BIG LOTS INC COMMON STOCK USD.01 089302103 346 5,069 SH   SOLE   5,069 0 0
BIO RAD LABORATORIES A COMMON STOCK USD.0001 090572207 2,702 4,731 SH   SOLE   4,731 0 0
BIO TECHNE CORP COMMON STOCK USD.01 09073M104 1,095 2,868 SH   SOLE   2,868 0 0
BIODELIVERY SCIENCES INTL COMMON STOCK USD.001 09060J106 173 44,179 SH   SOLE   44,179 0 0
BIOGEN INC COMMON STOCK USD.0005 09062X103 1,683 6,017 SH   SOLE   6,017 0 0
BIOMARIN PHARMACEUTICAL INC COMMON STOCK USD.001 09061G101 165 2,190 SH   SOLE   2,190 0 0
BITE ACQUISITION CORP UNIT USD.0001 09175K204 494 50,000 SH   SOLE   50,000 0 0
BJ S WHOLESALE CLUB HOLDINGS COMMON STOCK USD.01 05550J101 2,047 45,626 SH   SOLE   45,626 0 0
BLACKLINE INC COMMON STOCK USD.01 09239B109 1,345 12,412 SH   SOLE   12,412 0 0
BLACKROCK INC COMMON STOCK USD.01 09247X101 10,380 13,767 SH   SOLE   13,767 0 0
BLACKSTONE GROUP INC/THE COMMON STOCK USD.00001 09260D107 8,534 114,498 SH   SOLE   114,498 0 0
BLINK CHARGING CO COMMON STOCK USD.001 09354A100 466 11,340 SH   SOLE   11,340 0 0
BLUEPRINT MEDICINES CORP COMMON STOCK USD.001 09627Y109 1,413 14,529 SH   SOLE   14,529 0 0
BLUERIVER ACQUISITION CORP UNIT USD.0001 G1261Q123 0 2 SH   SOLE   2 0 0
BLUERIVER ACQUISITION CORP A COMMON STOCK USD.0001 G1261Q107 194 19,998 SH   SOLE   19,998 0 0
BLUERIVER ACQUISITION CORP A BLUERIVER ACQUISIT A CW26 G1261Q115 4 6,666 SH   SOLE   6,666 0 0
BLUEROCK RESIDENTIAL GROWTH REIT USD.01 09627J102 255 25,239 SH   SOLE   25,239 0 0
BLUESCAPE OPPORTUNITIES AC A COMMON STOCK USD.0001 G1195N105 995 99,998 SH   SOLE   99,998 0 0
BLUESCAPE OPPORTUNITIES AC A BLUESCAPE OPPORTUNIT A CW26 G1195N113 75 49,999 SH   SOLE   49,999 0 0
BLUESCAPE OPPORTUNITIES ACQ UNIT USD.0001 G1195N121 0 2 SH   SOLE   2 0 0
BOEING CO/THE COMMON STOCK USD5.0 097023105 4,172 16,379 SH   SOLE   16,379 0 0
BOOKING HOLDINGS INC COMMON STOCK USD.008 09857L108 6,505 2,792 SH   SOLE   2,792 0 0
BOOZ ALLEN HAMILTON HOLDINGS COMMON STOCK USD.01 099502106 2,394 29,733 SH   SOLE   29,733 0 0
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VERINT SYSTEMS INC COMMON STOCK USD.001 92343X100 1,273 27,981 SH   SOLE   27,981 242 0
VERISIGN INC COMMON STOCK USD.001 92343E102 2,452 12,337 SH   SOLE   12,337 243 0
VERISK ANALYTICS INC COMMON STOCK USD.001 92345Y106 7,276 41,177 SH   SOLE   41,177 244 0
VERITEX HOLDINGS INC COMMON STOCK USD.01 923451108 1,037 31,704 SH   SOLE   31,704 245 0
VERIZON COMMUNICATIONS INC COMMON STOCK USD.1 92343V104 6,340 109,025 SH   SOLE   109,025 246 0
VERTEX PHARMACEUTICALS INC COMMON STOCK USD.01 92532F100 7,145 33,250 SH   SOLE   33,250 247 0
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VIACOMCBS INC CLASS B COMMON STOCK USD.001 92556H206 649 14,381 SH   SOLE   14,381 253 0
VIATRIS INC COMMON STOCK 92556V106 209 14,950 SH   SOLE   14,950 254 0
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VISA INC CLASS A SHARES COMMON STOCK USD.0001 92826C839 40,269 190,189 SH   SOLE   190,189 258 0
VISHAY INTERTECHNOLOGY INC COMMON STOCK USD.1 928298108 1,261 52,359 SH   SOLE   52,359 259 0
VISTA OUTDOOR INC COMMON STOCK USD.01 928377100 304 9,493 SH   SOLE   9,493 260 0
VISTEON CORP COMMON STOCK 92839U206 292 2,395 SH   SOLE   2,395 261 0
VISTRA CORP COMMON STOCK USD.01 92840M102 5,438 307,570 SH   SOLE   307,570 262 0
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WABTEC CORP COMMON STOCK USD.01 929740108 265 3,348 SH   SOLE   3,348 267 0
WALDENCAST ACQUISITION CORP UNIT USD.0001 G9460C126 400 40,000 SH   SOLE   40,000 268 0
WALGREENS BOOTS ALLIANCE INC COMMON STOCK USD.01 931427108 597 10,873 SH   SOLE   10,873 269 0
WALMART INC COMMON STOCK USD.1 931142103 11,415 84,041 SH   SOLE   84,041 270 0
WALT DISNEY CO/THE COMMON STOCK USD.01 254687106 29,929 162,199 SH   SOLE   162,199 271 0
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WARBURG PINCUS CAPITAL CORP UNIT USD.0001 G9461D123 202 20,000 SH   SOLE   20,000 273 0
WARRIOR TECHNOLOGIES ACQUISI UNIT USD.0001 936273200 1,980 200,000 SH   SOLE   200,000 274 0
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WASTE MANAGEMENT INC COMMON STOCK USD.01 94106L109 724 5,612 SH   SOLE   5,612 276 0
WATERS CORP COMMON STOCK USD.01 941848103 875 3,079 SH   SOLE   3,079 277 0
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WEC ENERGY GROUP INC COMMON STOCK USD.01 92939U106 874 9,339 SH   SOLE   9,339 280 0
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WELLS FARGO CO COMMON STOCK USD1.666 949746101 2,744 70,236 SH   SOLE   70,236 282 0
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