Consolidated Statements of Operations - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2021	Dec. 31, 2020
Total revenues	$ 230	$ 168
Operating expenses:
Research and development	16,246	9,206
General and administrative	15,331	17,265
Total operating expenses	31,577	26,471
Loss from operations	(31,347)	(26,303)
Other income and expense:
Other income, net	269	6,467
Interest income	12	200
Other income, net	281	6,667
Net loss before taxes	(31,066)	(19,636)
Income tax benefit	636	13,973
Net loss	(30,430)	(5,663)
Accretion of preferred stock to current redemption value	0	(651)
Net loss attributable to common shareholders	$ (30,430)	$ (6,314)
Earnings Per Share [Abstract]
Basic (in dollars per share)	$ (3.65)	$ (0.93)
Diluted (in dollars per share)	$ (3.65)	$ (0.93)
Weighted average number of common shares outstanding
Basic (in shares)	8,334,516	6,777,932
Diluted (in shares)	8,334,516	6,777,932
Licensing and collaboration revenue
Revenues	$ 10	$ 168
Royalty revenue
Revenues	$ 220	$ 0