Condensed Consolidated Statements of Operations - USD ($)	3 Months Ended		6 Months Ended
	Jun. 30, 2016	Jun. 30, 2015	Jun. 30, 2016	Jun. 30, 2015
Grant revenue	$ 1,262,000	$ 3,280,000	$ 5,600,000	$ 12,929,000
Licensing and collaboration revenue	750,000	4,165,000	2,120,000	33,711,000
Total operating revenues	2,012,000	7,445,000	7,720,000	46,640,000
Operating expenses:
Research and development	27,410,000	16,130,000	49,347,000	34,111,000
General and administrative	9,130,000	7,257,000	18,294,000	15,623,000
Total operating expenses	36,540,000	23,387,000	67,641,000	49,734,000
Loss from operations	(34,528,000)	(15,942,000)	(59,921,000)	(3,094,000)
Other income and expense:
Interest income	(66,000)	(26,000)	(112,000)	(43,000)
Interest expense	6,000	4,000	13,000	10,000
Other income, net	60,000	22,000	99,000	33,000
Net loss before taxes	(34,468,000)	(15,920,000)	(59,822,000)	(3,061,000)
Income tax benefit	2,079,000	1,829,000	3,713,000	160,000
Net loss	$ (32,389,000)	$ (14,091,000)	$ (56,109,000)	$ (2,901,000)
Basic and diluted loss per share	$ (1.12)	$ (0.49)	$ (1.94)	$ (0.10)
Basic and diluted average shares outstanding	28,891,827	28,661,588	28,874,385	28,408,474