CONSOLIDATED STATEMENTS OF STOCKHOLDERS' EQUITY - USD ($) $ in Thousands	Total	Common Stock	Additional Paid-In Capital	Accumulated Deficit	Accumulated Other Comprehensive Loss
Beginning balance (in shares) at Dec. 31, 2022		61,701,467
Beginning balance at Dec. 31, 2022	$ 142,013	$ 617	$ 1,235,095	$ (1,093,694)	$ (5)
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Share-based compensation	4,788		4,788
Stock plan activity (in shares)		42,098
Stock plan related activity	(154)		(154)
Issuance of common stock, net of offering costs (in shares)		95,000
Issuance of common stock, net of offering costs	617	$ 1	616
Unrealized gain (loss) on investments	13				13
Net loss	(38,009)			(38,009)
Ending balance (in shares) at Mar. 31, 2023		61,838,565
Ending balance at Mar. 31, 2023	109,268	$ 618	1,240,345	(1,131,703)	8
Beginning balance (in shares) at Dec. 31, 2022		61,701,467
Beginning balance at Dec. 31, 2022	142,013	$ 617	1,235,095	(1,093,694)	(5)
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Net loss	19,460
Ending balance (in shares) at Jun. 30, 2023		61,938,493
Ending balance at Jun. 30, 2023	171,544	$ 619	1,245,231	(1,074,234)	(72)
Beginning balance (in shares) at Mar. 31, 2023		61,838,565
Beginning balance at Mar. 31, 2023	109,268	$ 618	1,240,345	(1,131,703)	8
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Share-based compensation	4,436		4,436
Stock plan related activity		$ 1
Stock plan activity (in shares)		63,793
Stock plan related activity	216		215
Issuance of common stock, net of offering costs (in shares)		36,135
Issuance of common stock, net of offering costs	235		235
Unrealized gain (loss) on investments	(80)				(80)
Net loss	57,469			57,469
Ending balance (in shares) at Jun. 30, 2023		61,938,493
Ending balance at Jun. 30, 2023	171,544	$ 619	1,245,231	(1,074,234)	(72)
Beginning balance (in shares) at Dec. 31, 2023		62,070,627
Beginning balance at Dec. 31, 2023	152,613	$ 621	1,254,750	(1,102,752)	(6)
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Share-based compensation	5,512		5,512
Stock plan related activity		$ 5
Stock plan activity (in shares)		489,875
Stock plan related activity	248		243
Unrealized gain (loss) on investments	(29)				(29)
Net loss	(52,190)			(52,190)
Ending balance (in shares) at Mar. 31, 2024		62,560,502
Ending balance at Mar. 31, 2024	106,154	$ 626	1,260,505	(1,154,942)	(35)
Beginning balance (in shares) at Dec. 31, 2023		62,070,627
Beginning balance at Dec. 31, 2023	$ 152,613	$ 621	1,254,750	(1,102,752)	(6)
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Shares, Granted (in shares)	1,903,482
Net loss	$ (107,854)
Ending balance (in shares) at Jun. 30, 2024		62,720,969
Ending balance at Jun. 30, 2024	57,819	$ 627	1,267,822	(1,210,606)	(24)
Beginning balance (in shares) at Mar. 31, 2024		62,560,502
Beginning balance at Mar. 31, 2024	106,154	$ 626	1,260,505	(1,154,942)	(35)
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Share-based compensation	6,693		6,693
Stock plan related activity		$ 1
Stock plan activity (in shares)		160,467
Stock plan related activity	625		624
Unrealized gain (loss) on investments	11				11
Net loss	(55,664)			(55,664)
Ending balance (in shares) at Jun. 30, 2024		62,720,969
Ending balance at Jun. 30, 2024	$ 57,819	$ 627	$ 1,267,822	$ (1,210,606)	$ (24)