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Summary of Significant Accounting Policies - Summary of Collaborators that Represent More Than 10% of Total Revenue Earned (Details) - Sales revenue, net - Customer Concentration Risk
12 Months Ended
Dec. 31, 2018
Dec. 31, 2017
Dec. 31, 2016
Incyte Corporation (Incyte)      
Concentration Risk [Line Items]      
Percentage of all significant revenue earned 68.00% 96.00% 0.00%
Janssen Biotech, Inc. (Janssen)      
Concentration Risk [Line Items]      
Percentage of all significant revenue earned     85.00%
Provention Bio, Inc. (Provention)      
Concentration Risk [Line Items]      
Percentage of all significant revenue earned 10.00% 0.00% 0.00%