Condensed Consolidated Balance Sheets - USD ($) $ in Thousands	Mar. 31, 2023	Dec. 31, 2022
Current assets:
Cash and cash equivalents	$ 421,365	$ 242,493
Marketable securities	277,282	389,564
Accounts receivable, net	183,371	158,043
Inventory	124,092	118,259
Prepaid expenses and other current assets	85,274	73,898
Total current assets	1,091,384	982,257
Long-term Assets:
Property, plant and equipment, net	684,574	684,756
Operating lease right-of-use assets	156,782	167,003
Goodwill	2,346,235	2,346,040
Intangible assets, net	1,933,481	1,956,240
Other long-term assets, net	91,872	90,577
Total assets	6,304,328	6,226,873
Current liabilities:
Accounts payable	86,713	74,916
Accrued liabilities	241,844	299,216
Operating lease liabilities, current portion	30,014	28,366
Other current liabilities	8,783	10,249
Total current liabilities	367,354	412,747
Long-term liabilities:
Convertible notes, net	2,310,196	2,186,106
Long-term debt	50,000	50,000
Other long-term liabilities	344,380	352,459
Operating lease liabilities, less current portion	174,690	182,399
Total liabilities	3,246,620	3,183,711
Commitments and contingencies (Note 14)
Stockholders’ equity:
Preferred stock, $0.01 par value Authorized—5,000,000; shares issued and outstanding—no shares at March 31, 2023 and December 31, 2022	0	0
Common stock, $0.01 par value Authorized—400,000,000; shares issued and outstanding—179,830,145 and 177,925,631 shares at March 31, 2023 and December 31, 2022	1,799	1,780
Additional paid-in capital	6,396,805	6,311,644
Accumulated other comprehensive loss	(1,719)	(5,236)
Accumulated deficit	(3,339,177)	(3,265,026)
Total stockholders’ equity	3,057,708	3,043,162
Total liabilities and stockholders’ equity	$ 6,304,328	$ 6,226,873