SHAREHOLDERS' EQUITY (Tables)

12 Months Ended

Dec. 31, 2022

Stockholders' Equity Note [Abstract]

Schedule of stock-based compensation expenses

Transactions related to the grant of options to employees, directors and non-employees under the above Plan during the year ended December 31, 2022, were as follows:

	Number of options			Weighted average exercise price		Weighted average remaining contractual life		Aggregate intrinsic value
				$		Years		$
Options outstanding at beginning of year		6,976,104			6.39		6.69		3,323
Options granted		2,186,400			2.58
Options exercised		(33,186	)		3.14
Options forfeited		(778,069	)		6.42
Options expired		(193,500	)		4.21
Options outstanding at end of year		8,157,749			5.43		6.32		-
Exercisable at end of year		4,635,040			5.68		4.52		-

Schedule of option activity

e.The stock-based compensation expenses related to stock options and ESPP are included as follows in the expense categories:

	Year ended December 31,
	2022		2021		2020
Research and development expenses	$	2,158	$	1,971	$	1,123
Marketing and business development expenses		269		215		172
General and administrative expenses		1,901		2,090		1,477
	$	4,328	$	4,276	$	2,772