SEC Form 3

FORM 3

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 INITIAL STATEMENT OF BENEFICIAL OWNERSHIP OF SECURITIES Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the Investment Company Act of 1940

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1. Name and Address of Reporting Person* LaSpaluto Michelle (Last) (First) (Middle) C/O CHIMERIX, INC. 2505 MERIDIAN PKWY, SUITE 100 (Street) DURHAM NC 27713 (City) (State) (Zip)	2. Date of Event Requiring Statement (Month/Day/Year) 12/01/2023	3. Issuer Name and Ticker or Trading Symbol CHIMERIX INC [ CMRX ]
		4. Relationship of Reporting Person(s) to Issuer (Check all applicable) Director 10% Owner X Officer (give title below) Other (specify below) Chief Financial Officer	5. If Amendment, Date of Original Filed (Month/Day/Year)
			6. Individual or Joint/Group Filing (Check Applicable Line) X Form filed by One Reporting Person Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Beneficially Owned
1. Title of Security (Instr. 4)	2. Amount of Securities Beneficially Owned (Instr. 4)	3. Ownership Form: Direct (D) or Indirect (I) (Instr. 5)	4. Nature of Indirect Beneficial Ownership (Instr. 5)
Common Stock	87,939(1)	D

Table II - Derivative Securities Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 4)	2. Date Exercisable and Expiration Date (Month/Day/Year)		3. Title and Amount of Securities Underlying Derivative Security (Instr. 4)		4. Conversion or Exercise Price of Derivative Security	5. Ownership Form: Direct (D) or Indirect (I) (Instr. 5)	6. Nature of Indirect Beneficial Ownership (Instr. 5)
	Date Exercisable	Expiration Date	Title	Amount or Number of Shares
Stock Option (Right to Buy)	(2)	01/27/2024	Common Stock	9,000	$18.75	D
Stock Option (Right to Buy)	(2)	12/03/2024	Common Stock	750	$36.75	D
Stock Option (Right to Buy)	(2)	01/27/2025	Common Stock	9,000	$39.41	D
Stock Option (Right to Buy)	(2)	07/31/2025	Common Stock	1,500	$53.74	D
Stock Option (Right to Buy)	(2)	07/31/2025	Common Stock	15,000	$53.74	D
Stock Option (Right to Buy)	(2)	01/07/2026	Common Stock	18,700	$8.06	D
Stock Option (Right to Buy)	(2)	12/14/2026	Common Stock	1,250	$4.51	D
Stock Option (Right to Buy)	(2)	01/24/2028	Common Stock	13,000	$4.68	D
Stock Option (Right to Buy)	(2)	01/22/2029	Common Stock	8,098	$2.41	D
Stock Option (Right to Buy)	(2)	09/25/2029	Common Stock	48,438	$2.49	D
Stock Option (Right to Buy)	01/21/2020(3)	01/20/2030	Common Stock	62,067	$2.08	D
Stock Option (Right to Buy)	01/22/2021(4)	01/21/2031	Common Stock	90,000	$9.28	D
Stock Option (Right to Buy)	01/18/2022(4)	01/17/2032	Common Stock	95,000	$5.62	D
Stock Option (Right to Buy)	01/17/2023(4)	01/16/2033	Common Stock	64,275	$1.97	D

Explanation of Responses:

1. Amount includes 10,725 unvested shares pursuant to a restricted stock unit award issued on January 17, 2023.

2. Fully vested and exercisable.

3. 1/48th of the shares will vest each month over a four year period following the vesting commencement date. This stock option was previously exercised as to 25,933 shares.

4. 1/48th of the shares will vest each month over a four year period following the vesting commencement date.

Remarks:

	/s/ Michael Alrutz, Attorney-in-Fact	12/04/2023
	** Signature of Reporting Person	Date
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 5 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
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