Income Taxes (Reconciliation of the Difference between the Benefit for Income Taxes and Income Taxes at the Statutory U.S. Federal Income Tax Rate) (Alternate) (Details) - USD ($)	12 Months Ended
	Dec. 31, 2022	Dec. 31, 2021	Dec. 31, 2020
Amount
Income tax benefit at statutory rate	$ 36,163,000	$ (36,379,000)	$ (9,140,000)
State income taxes	441,000	(8,060,000)	(138,000)
Research and development credits	(3,312,000)	(1,565,000)	(1,088,000)
In process R&D	0	26,395,000	0
Permanent items	1,135,000	711,000	505,000
Provision to return adjustments	1,091,000	126,000	81,000
Effect of change in federal tax rate	0	0	0
Effect of change in state tax rate	4,405,000	3,478,000	1,139,000
Removal of excess tax benefit	0	0	0
Increase in unrecognized tax benefits	828,000	439,000	272,000
Current year forfeitures	54,000	435,000	4,026,000
Change in valuation allowance	(40,769,000)	14,420,000	4,343,000
Net benefit	$ 36,000	$ 0	$ 0
% of Pretax Earnings
Income tax benefit at statutory rate	21.00%	21.00%	21.00%
State income taxes	0.20%	4.70%	0.30%
Research and development credits	(1.90%)	0.90%	2.50%
In process R&D	0.00%	(15.20%)	0.00%
Permanent items	0.70%	(0.40%)	(1.20%)
Provision to return adjustments	0.60%	(0.10%)	(0.20%)
Effect of change in federal tax rate	0.00%	0.00%	0.00%
Effect of change in state tax rate	2.60%	(2.00%)	(2.60%)
Removal of excess tax benefit	0.00%	0.00%	0.00%
Increase in unrecognized tax benefits	0.50%	(0.30%)	(0.60%)
Current year forfeitures	0.00%	(0.30%)	(9.20%)
Change in valuation allowance	(23.70%)	(8.30%)	(10.00%)
Net benefit	0.00%	0.00%	0.00%