Restructuring Costs (Tables)

6 Months Ended

Jun. 30, 2019

Restructuring and Related Activities [Abstract]

Restructuring and Related Costs

The following table summarizes the restructuring charges (in thousands) recorded for the three months ended June 30, 2019:

	Employee Termination Benefits	Clinical Trial Close-out Costs	Other Development Costs	Total
Research and development	1,426	2,837	315	4,578
General and administrative	1,909	—	—	1.909
Total restructuring expenses	3,335	2,837	315	6,487

Schedule of Restructuring Reserve by Type of Cost

The following table sets forth the accrual activity for employee termination benefits and contract close-out costs (in thousands) for the three months ended June 30, 2019. No additional charges are expected to be incurred.

	Employee Termination Benefits		Clinical Trial Close-out Costs		Other Development Costs	Total
Balance at March 31, 2019	—		—		—	—
Accruals	3,335		2,131		315	5,781
Payments	(1,551	)	(69	)	—	(1,620	)
Balance at June 30, 2019	1,784		2,062		315	4,161