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Investments - Schedule of Investment Maturity (Details) (USD $)
In Thousands, unless otherwise specified
Mar. 31, 2015
Dec. 31, 2014
Investments, Debt and Equity Securities [Abstract]    
Maturing in one year or less $ 118,898us-gaap_AvailableForSaleSecuritiesDebtMaturitiesWithinOneYearFairValue  
Maturing after one year through two years 95,239cmrx_AvailableforSaleSecuritiesDebtMaturitiesYearOnethroughTwoFairValue  
Total investments $ 214,137us-gaap_AvailableForSaleSecurities $ 159,087us-gaap_AvailableForSaleSecurities