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Loss Per Share (Tables)
3 Months Ended
Mar. 31, 2018
Schedule of Earnings Per Share, Basic and Diluted [Table Text Block]
      Three months ended March 31,  
      2017     2018  
  Net loss $ (2,068,216 ) $ (2,567,833 )
               
  Weighted average shares used in basic and diluted computation (note)   19,856,778     26,502,086  
               
  Loss per share $ (0.10 ) $ (0.10 )