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[The following materials were provided to certain stockholders of Bruker BioSciences Corporation beginning on June 5, 2006.]

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Searchable text section of graphics shown above

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Bruker BioSciences Corporation (BRKR)

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Presentation for BRKR Shareholders on Planned Acquisition of Bruker Optics Inc. June 5 & 6, 2006

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Bruker BioSciences:

Frank Laukien, CEO

Bill Knight, CFO

Brian Monahan, Controller

Bruker Optics:

Dirk Laukien, CEO

Dan Klevisha, VP

Safe Harbor Statement of BRKR

Any statements contained in this presentation that do not describe historical facts may constitute forward-looking statements as that term is defined in the Private Securities Litigation Reform Act of 1995. Any forward-looking statements contained herein are based on current expectations, but are subject to a number of risks and uncertainties. The factors that could cause actual future results to differ materially from current expectations include, but are not limited to, risks and uncertainties relating to the companies’ reorganization strategies, integration risks, failure of conditions, technological approaches, product development, market acceptance, cost and pricing of the companies’ products, changes in governmental regulations, capital spending and government funding policies, FDA and other regulatory approvals to the extent applicable, competition, the intellectual property of others, patent protection and litigation. We do not undertake, and expressly disclaim, any obligation to update this forward-looking information except as required by law. For details regarding factors that could cause actual results to differ materially from those anticipated, please refer to our SEC filings, including our Annual Report on Form 10-K for the year ended December 31, 2005.

Please read BRKR Definitive Proxy Statement filed with the SEC on May 25, 2006.

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Overview of Presentation

•	Transaction Overview and Rationale
•	Bruker Optics Highlights
•	Bruker BioSciences Today & Tomorrow
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Transaction Overview

BRKR becomes a >$400M revenue leading provider of

•high-performance analytical and life-science systems for molecular and materials research, and

•applications-driven robust analytical solutions for industry.

•Purchase price for Bruker Optics: $135M

•Cash: $79.2M (59%)

•BRKR stock: $55.8M (41%), estimated 10.4M shares

•Final # of shares depends on 10-day average BRKR closing price until 3 days prior to Closing

•Accounting (common ownership): pooling of interests

•Acquisition charges expensed

•Negligible goodwill and intangibles

•Restated pro-forma historical financials

•Cash of BRKR after Closing:

•$20M in new debt

•Total cash approx. $50M

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Transaction Overview

Deal is Accretive:

•Historical pro-forma EPS accretion of $0.01-$0.02

	FY 2005		FY 2004			FY 2003
EPS, as reported	$	0.04	$	(0.09	)	$	(0.22	)
EPS, pro forma	$	0.06	$	(0.08	)	$	(0.21	)

•Going forward, BRKR expects accretion to GAAP EPS:

•2006 by approx. $0.01 (Non-GAAP by approx. $0.03)

•2007 by $0.03-$0.05

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Process & Schedule:

•Negotiated and approved by Special Committee (SC) of independent BRKR directors

•Advisory services to SC and fairness opinion rendered by Bear Stearns

•Legal advice to SC from independent counsel Dewey Ballantine

•Requires approval by:

•majority of voting BRKR shareholders, and

•majority of voting non-affiliated BRKR shareholders

•Closing: expected in early Q3 2006

•Relevant HSR approvals already received

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Transaction Rationale

•Increased market access

•additional >$500M accessible markets, >$80M revenue

•access to fast growth markets PAT, pharma forensics

•better demand diversification, higher industrial revenue

•Expanded technology base and product line

•adds molecular spectroscopy technology: IR, NIR, Raman

•adds broad product line with applications solution

•adds time-domain NMR analyzer distribution

•Broader marketing footprint

•enhanced global distribution and customer support

•increased brand leverage

•cross-selling opportunities

•Financial expectations (supported by historical 2005 pro forma)

•improved gross, operating and net income margins

•increased operating cash flows

•immediately accretive

•Good partial use of BRKR $100M balance sheet cash

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Bruker Optics Highlights

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Bruker Optics Inc.

A leading provider of molecular spectroscopy tools and solutions

FT-IR FT-NIR Raman TD-NMR

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Bruker Optics Management

Name and Position	Years in Industry		Years at Bruker
Dirk D. Laukien, Ph.D. Chairman, President and CEO	15	+	15	+
Arno Simon, Ph.D. Vice President, R & D, Director Optik GmbH	25	+	25	+
Daniel Klevisha Vice President, Marketing & Sales	15	+	10
Qian Wang, Ph.D. Vice President, NIR, Director Asia Pacific	15	+	10
Rolf Lang CFO, Director Optik GmbH	15	+	5
Frank Mueller Production Manager, Director Optik GmbH	9		9
Jonathan D. Hitchcock Treasurer and Controller, Director Asia Pacific	6		6

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Bruker Optics Key Markets

	Leading technology for molecular spectroscopy and materials research	[GRAPHIC]
		Academic and Government
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	Industrial R&D
[GRAPHIC] Laboratory Analysis	Developing advanced measurements into routine analysis tools	Bruker Optics accessible markets: >$500M p.a.

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[GRAPHIC]	Enabling real-time science-based control of pharmaceutical manufacturing process
Pharmaceutical Process Analytical Technologies (PAT)	[GRAPHIC]
	Chemical, Polymer Analysis	[GRAPHIC]
	Rapid analysis for food quality traits & feed optimization	Food, Feed and Agricultural Analysis

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Bruker Optics Customers Include:

Life Science	Analytical	Process
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In addition, Bruker Optics has a significant presence in most large academic and national research laboratories.

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Bruker Optics Leading Technologies

>30 years of Molecular Spectroscopy Leadership:

1974 Delivery of the first FT-IR spectrometer

1976 Modular vacuum research FT-IR spectrometer

1981 First FT-IR spectrometer for industrial routine

1984 First FT-IR microscope

1985 IFS 120 - Highest resolution FT-IR spectrometer

1988 R&D award for StepScan Technology

1988 FT-Raman Products Launched

1993 Dedicated FT-NIR Spectrometers

1996 Life Science Applications

2000 R&D award for dedicated process FT-NIR

2001 Imaging system with focal plane array detector

2004 “iF” Design Award for MPA FT-NIR spectrometer

2005 Senterra Dispersive Raman Microscope

2005 FT-NIR Feed Analyzer

2006 VERTEX 80v High-Resolution Vacuum Research FTIR

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Bruker Optics Products

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FT-IR and Raman Spectrometers

Applications:

•Routine Quality Control Applications

•Academic and Industrial R&D

•Drug Discovery (Proteomics)

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Near Infrared Spectrometers

Applications:

•Routine Quality Control Applications

•Pharmaceutical Raw Material ID, Tablet Testing and Identification

•Food/Feed/Agriculture Quality control

•Pharma-Forensics, Fake Drug Analysis

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Time Domain NMR Analyzers

Applications:

•Food, Edible Oil and Grain Analysis QC

•Textile Analysis

•Live Animal Testing for Body Fat Studies

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Microspectroscopy Solutions

•Based on FT-IR and Raman Microscopy

Applications:

•Contamination Analysis

•Forensics

•Art Conservation

•Materials Research

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Process Analyzers

•Based on FT-IR, FT-NIR and Raman Systems

Real-time QC during all stages of manufacturing:

•Chemical Industry

•Petrochemical industry

•Pharma PAT (Process Analytical Technology)

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Bruker Optics New Opportunities

Pharma/biotech PAT: Process Analytical Technologies

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Factory Shift *

New Prescription

For Drug Makers:

Update the Plants

After Years of Neglect, Industry

Focuses on Manufacturing;

FDA Acts as a Catalyst

Pharma/biotech PAT:

“Enabling real-time, science based

process control to improve product

quality, reduce risk and improve

manufacturing efficiency”

•Bruker Optics technologies are highly applicable to PAT

•Bruker Optics seized this opportunity and became a PAT leader

•Placement in 23 of the top 25 pharma companies

* Front page Wall Street Journal Article dated September 3, 2003.

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“Pharma Forensics”:
Chinese SFDA Battling Fake Drugs

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Front page Wall Street Journal Article in 2006.

Bruker Optics SFDA order in 2006:

•300+ Unit Order valued at >$15M in revenue

•Largest project of its kind in China

•Largest single order for Bruker Optics

•Good chances for follow-up business globally

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Bruker Optics Revenue

Strong organic

revenue growth

in 2001-2005:

CAGR of 23%

[CHART]

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Bruker Optics Margins & Income

[CHART]

	2005		‘01 - ‘05
	% of Revenue		CAGR
Adjusted EBITDA	19	%	44	%
Operating Income	15	%	46	%
Net Income	8	%	47	%

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Bruker Optics Adjusted EBITDA

(in $M)

	2001		2002		2003		2004		2005
Operating Income	$	2.7	$	3.7	$	4.0	$	7.7	$	12.0
Depreciation and amortization	0.5		0.8		1.7		1.4		1.9
Write-down of demonstration equipment	0.3		0.5		1.2		1.4		1.2
Adjusted EBITDA	$	3.5	$	5.0	$	6.9	$	10.5	$	15.1

USE OF NON-GAAP FINANCIAL MEASURES: In addition to the financial measures prepared in accordance with generally accepted accounting principles (GAAP), we use the non-GAAP measure of Adjusted EBITDA, defined as US GAAP operating income excluding depreciation and amortization expense and the write-down of demonstration equipment to net realizable value. We believe that the inclusion of this non-GAAP measure helps investors gain a better understanding of our core operating results and future prospects, consistent with how management measures and forecasts the Company’s performance, especially when comparing such results to previous periods or forecasts.

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BRKR Today & Tomorrow

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A leading provider of

•high-performance analytical and life-science systems for molecular and materials research,

•applications-driven robust analytical solutions for industry

“Innovation for Customers, Delivered with Integrity”

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Post-Acquisition Industrial Markets with Strong Marketing Synergies

Market & Application	Industrial Customers	BDAL	BAXS	BOPT
Drug Discovery & Development (DDD)	Pharma, biotech & diagnostics	[GRAPHIC] DDD-Responsibility	BDAL to assist BAXS in DDD market	BDAL to market FTIR for drug discovery, proteomics
Process Analytical Technology (PAT) Pharma Forensics	Pharma, biotech & generics	BOPT to market BDAL MS & IMS for PAT	BOPT to market BAXS XRD & XRF for PAT	[GRAPHIC] PAT-Responsibility
Materials Science & Analysis (MSA)	Adv. materials, semicon, oil, cement, metal	No products	[GRAPHIC] MSA-Responsibility	BAXS to market FTIR cement, oil analyzers, IR wafer system
Food, Feed & Agriculture (FFA)	Food & Beverage, Agricultural	BOPT to market BDAL MS for food safety	assists BOPT in FFA market	[GRAPHIC] FFA-Responsibility

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BRKR Stand-Alone Trends

		Q1-06			2005			2004
•	Revenue	$	74.4	M	$	297.6	M	$	284.4	M
•	Op. Income	$	3.0	M*	$	10.6	M	$	(1.1	)M
•	Adjusted EBITDA	$	6.6	M	$	26.9	M	$	16.8	M
•	Net Income	$	1.8	M*	$	3.6	M	$	(7.8	)M
•	EPS	$	0.02	*	$	0.04		$	(0.09	)

(* Non-GAAP Operating Income, Net Income and EPS in Q1-06 exclude acquisition related charges of $1.2M pretax, $1.0M after tax)

•Solid improvements with 5 profitable quarters

•> $40M cash generated from operations in 2005

•Significant operating cash flow in 2005

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BRKR 2005 Actual vs. Pro-Forma

		2005			2005 Pro-Forma
		Actual			Combined
•	Revenue	$	297.6	M	$	372.3	M
•	Op. Income	$	10.6	M	$	21.7	M
•	Adjusted EBITDA	$	26.9	M	$	41.1	M
•	Net Income	$	3.6	M	$	5.6	M
•	EPS	$	0.04		$	0.06
•	Op. Cash Flow	$	42.2	M	$	49.7	M

Unaudited Pro-Forma Combined Financials give effect to the acquisition as if it had been completed on January 1, 2005.

• Acquisition creates larger, more profitable BRKR with increased margins and operating cash flows.

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BRKR Adjusted EBITDA

(in $M)

	Q1-06 Actual		2005 Actual		2004 Actual			2005Pro-Forma Combined
Operating Income	$	1.8	$	10.6	$	(1.1	)	$	21.7
Depreciation and amortization	2.1		8.6		9.5			10.5
Write-down of demonstration equipment	1.5		7.7		8.4			8.9
Acquisition related charges	1.2		—		—			—
Adjusted EBITDA	$	6.6	$	26.9	$	16.8		$	41.1

USE OF NON-GAAP FINANCIAL MEASURES: In addition to the financial measures prepared in accordance with generally accepted accounting principles (GAAP), we use the non-GAAP measure of Adjusted EBITDA, defined as US GAAP operating income excluding depreciation and amortization expense, the write-down of demonstration equipment to net realizable value and acquisition related charges. We believe that the inclusion of this non-GAAP measure helps investors gain a better understanding of our core operating results and future prospects, consistent with how management measures and forecasts the Company’s performance, especially when comparing such results to previous periods or forecasts.

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BRKR Drivers & Goals 2006-2008

•Innovation: even more significant driver within our markets

•Growth: above industry-standard (organic and bolt-ons)

•Gross margin initiative 2006-2008:

•RTC and more in-house core technologies

•Higher margin after-market revenue

•More complete solutions

•Higher margin new products

•Expense leverage: 2000-05 enormous R&D, M&S investment

•Significant expense leverage

•Balance sheet, cash flow:

•Continuing reduction in effective tax rate

•Continued strong free cash flow

•Profitability: reach industry-standard (and above)

•The acquisition of Bruker Optics accelerates BRKR’s drive towards these goals in all aspects.

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BRKR Growth & Strategy

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1995: BDAL was private European $30M company

•Bruker Daltonics faced stagnating NBC detection markets

•$5.6M U.S. revenue, virtually no Asian revenue

•$7.5M life-science revenue (25%), 3 products

•1997: acquired $50M AXS business from Siemens: GM<35%, systems integrator with few core technologies

2005: BRKR is public ~$300M revenue company

•10-year build up of BDAL life-science technology, IP, product line, Proteineer™ and ClinProt™ solutions, global distribution

•$142M BDAL life-science revenue (88%), $50M US revenue

•Developed BAXS infrastructure, R&D, technology base, product line, global distribution to $137M (GM 39%)

•BAXS entered bio-SCD, EDXRF industrial market, microanalysis, became XRD market leader, #2 in JP

•BDAL-BAXS merged into BRKR in 2003

•2005: BRKR profitable, ~$42M op. cash flow, ~$100M year-end cash balance

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BRKR Growth & Strategy

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BRKR with Bruker Optics in 2006 and beyond: >$400M revenue

•Leverage marketing and distribution synergies of BRKR

•Maintain very innovative R&D and engineering processes: differentiated high-performance, high quality products with excellent brand recognition

•Strong IP position in technologies with high barriers to entry

•Increasing focus on solutions for customer-driven applications

•Continue to drive above-average organic growth

•Selective acquisitions, leveraging Bruker-brand and global distribution

•Continue to build world-class organization

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BRKR Growth & Strategy

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Combined Opportunities for Dramatic Growth:

•Molecular tools: chemistry, metabolomics, proteomics, structural biology

•Clinical research tools: biomarkers, molecular imaging, IVD, personalized medicine, theranostics, infectious disease

•Pharma/biotech: drug discovery, drug development, biomarkers, pharmacoproteomics, PAT, pharma forensics

•Materials research: advanced materials, composites, thin films, nanotechnology

•Industrial analysis: semicon research and FABs, petroleum, polymers, metals industry, cement industry

•Food, beverage and agricultural analysis

•New NBC detection opportunities in homeland security

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