Condensed Consolidated Statements of Operations and Comprehensive Loss - USD ($) $ in Thousands	3 Months Ended		9 Months Ended
	Sep. 30, 2016	Sep. 30, 2015	Sep. 30, 2016	Sep. 30, 2015
Revenues:
Royalties	$ 1,817	$ 2,293	$ 5,403	$ 5,998
Research and development, net	(58)	(248)	(238)	(212)
Total revenues	1,759	2,045	5,165	5,786
Costs and expenses:
Cost of royalty revenues	94	116	278	303
Research and development	6,781	4,001	22,431	14,658
In-process research and development	17,989	0	17,989	24,348
General and administrative	4,684	2,772	11,743	9,712
Total costs and expenses	29,548	6,889	52,441	49,021
Loss from operations	(27,789)	(4,844)	(47,276)	(43,235)
Other expense:
Interest income	101	128	325	252
Interest expense	(657)	(827)	(2,126)	(2,537)
Total other expense, net	(556)	(699)	(1,801)	(2,285)
Net loss	$ (28,345)	$ (5,543)	$ (49,077)	$ (45,520)
Net loss per common share (basic and diluted) (in dollars per share)	$ (0.21)	$ (0.04)	$ (0.38)	$ (0.37)
Weighted average common shares (basic and diluted) (in shares)	132,065,947	128,392,413	130,122,698	121,634,415
Total comprehensive loss	$ (28,376)	$ (5,488)	$ (49,079)	$ (45,456)