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Collaboration Agreements - Additional Information (Detail) (USD $)
3 Months Ended 9 Months Ended 1 Months Ended 3 Months Ended 9 Months Ended 1 Months Ended 3 Months Ended 9 Months Ended 1 Months Ended 9 Months Ended
Sep. 30, 2014
Sep. 30, 2013
Sep. 30, 2014
Sep. 30, 2013
Dec. 31, 2013
May 31, 2013
Genentech Inc [Member]
Sep. 30, 2014
Genentech Inc [Member]
Sep. 30, 2013
Genentech Inc [Member]
Sep. 30, 2014
Genentech Inc [Member]
Licensors
Sep. 30, 2013
Genentech Inc [Member]
Jun. 30, 2014
Genentech Inc [Member]
Nov. 30, 2011
Leukemia and Lymphoma Society [Member]
Sep. 30, 2014
Leukemia and Lymphoma Society [Member]
Sep. 30, 2014
Leukemia and Lymphoma Society [Member]
Sep. 30, 2013
Leukemia and Lymphoma Society [Member]
Sep. 30, 2014
Minimum [Member]
Genentech Inc [Member]
Sep. 30, 2014
Maximum [Member]
Genentech Inc [Member]
Nov. 30, 2011
Maximum [Member]
Leukemia and Lymphoma Society [Member]
Sep. 30, 2014
Maximum [Member]
Leukemia and Lymphoma Society [Member]
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]                                      
Earned milestone payment                 $ 3,000,000     $ 1,650,000     $ 650,000        
Eligibility to receive contingent cash milestone payments under the collaboration             115,000,000   115,000,000                    
Earned milestone payment           4,000,000                          
Amount earned for specified clinical development and regulatory objectives             59,000,000   59,000,000                    
License fees 0 6,000,000 3,000,000 10,000,000       6,000,000 3,000,000 10,000,000                  
Milestone amounts included accounts receivable 1,839,319   1,839,319   1,477,188           3,000,000                
Number of university licensors in connection with the FDA-approval of Erivedge                 2                    
Research and development expenses 3,705,365 4,170,751 10,180,271 9,965,847       300,000 150,000 500,000                  
Percentage of royalty rate escalation                               5.00% 7.50%    
Royalty portion of annual worldwide net sales                               150,000,000 600,000,000    
Percentage of royalty rate decrease                 2.00%                    
Percentage of royalty                               3.00% 5.50%    
Recognized royalty revenues 1,783,271 1,080,233 4,895,454 2,549,945     1,783,271 1,080,233 4,895,454 2,549,945                  
Costs of royalty revenues recorded 89,295 54,014 246,280 127,499     89,295 54,014 246,280 127,499                  
Percentage of royalties earned             5.00% 5.00% 5.00% 5.00%                  
Research and development revenue (18,407) 121,850 (44,672) 927,950     72,817 87,916 144,054 181,910                  
Contra-revenues             94,118   233,701                    
Contribution of fund from LLS amount                                   4,000,000  
Revenue recognized, milestone achieved upon treatment of first patient of phase one trial                         0 0 650,000        
Royalty obligation on successful progressing of CUDC - 907 through clinical trials                           $ 4,125,000         $ 10,000,000
Multiplier applied to milestone payments received to determine royalty obligation                           2.5