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Condensed Consolidated Statements of Cash Flows (Unaudited) (USD $)
6 Months Ended
Jun. 30, 2014
Jun. 30, 2013
CASH FLOWS FROM OPERATING ACTIVITIES:    
Net loss $ (7,459,721) $ (6,256,142)
Adjustments to reconcile net loss to net cash used in operating activities:    
Depreciation and amortization 74,837 67,734
Stock-based compensation expense 1,427,265 1,576,537
Change in fair value of warrant liability (648,876) (634,401)
Non-cash interest expense on investments 69,046 163,826
Amortization of debt issuance costs 52,427 52,389
Non-cash in-kind interest accrued on Curis Royalty's debt   582,062
Payment-in kind interest on Curis Royalty's debt (711,353)  
Changes in operating assets and liabilities:    
Accounts receivable (3,366,224) 44,877
Prepaid expenses and other assets 131,908 (34,941)
Accounts payable and accrued liabilities 395,205 133,810
Total adjustments (2,575,765) 1,951,893
Net cash used in operating activities (10,035,486) (4,304,249)
CASH FLOWS FROM INVESTING ACTIVITIES:    
Purchases of investments (25,347,887) (27,704,396)
Sales of investments 35,736,387 26,097,035
Purchases of property and equipment (58,861) (34,957)
Decrease in restricted cash 13,877 13,918
Net cash provided by/(used in) investing activities 10,343,516 (1,628,400)
CASH FLOWS FROM FINANCING ACTIVITIES:    
Proceeds from issuance of common stock under the Company's share-based compensation plans and warrant exercises 256,843 3,189,353
Payment of debt issuance costs   (261,475)
Net cash provided by financing activities 256,843 2,927,878
NET INCREASE/(DECREASE) IN CASH AND CASH EQUIVALENTS 564,873 (3,004,771)
CASH AND CASH EQUIVALENTS, BEGINNING OF PERIOD 9,591,487 12,747,709
CASH AND CASH EQUIVALENTS, END OF PERIOD $ 10,156,360 $ 9,742,938