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Revenue Recognition - Additional Information (Detail) - USD ($)
$ in Thousands
Jun. 30, 2018
Jan. 01, 2018
Dec. 31, 2017
May 31, 2015
Revenue, Initial Application Period Cumulative Effect Transition [Line Items]        
Accumulated deficit $ (748,624)   $ (712,442)  
Remaining contract liability related to two targets expected to be recognized within the next twelve months $ 0      
In Process Research and Development        
Revenue, Initial Application Period Cumulative Effect Transition [Line Items]        
Estimated period of performance 9 years      
ASU 2014-09        
Revenue, Initial Application Period Cumulative Effect Transition [Line Items]        
Accumulated deficit   $ (720,573)    
ARES Trading License        
Revenue, Initial Application Period Cumulative Effect Transition [Line Items]        
Deferred revenue, upfront payment       $ 57,500
Difference between Revenue Guidance in Effect before and after Topic 606 | ASU 2014-09        
Revenue, Initial Application Period Cumulative Effect Transition [Line Items]        
Accumulated deficit $ 11,180 $ (8,131)