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Restructuring - Additional Information (Detail) (USD $)
12 Months Ended 0 Months Ended 12 Months Ended 0 Months Ended
Dec. 31, 2013
Dec. 31, 2012
Aug. 30, 2013
sqft
Dec. 31, 2014
Oct. 17, 2013
sqft
Restructuring Cost and Reserve [Line Items]          
Restructuring charges $ 1,700,000us-gaap_RestructuringCharges        
Loss on disposition of business 800,000us-gaap_GainLossOnSaleOfBusiness        
Loss on disposal of fixed assets 600,000us-gaap_GainLossOnDispositionOfAssets1        
Loss on disposal of fixed assets (585,000)us-gaap_GainLossOnSaleOfPropertyPlantEquipment (48,000)us-gaap_GainLossOnSaleOfPropertyPlantEquipment      
Severance and Health Benefit Continuation Costs          
Restructuring Cost and Reserve [Line Items]          
Restructuring charges   1,300,000us-gaap_RestructuringCharges
/ us-gaap_RestructuringCostAndReserveAxis
= us-gaap_EmployeeSeveranceMember
     
Boston, MA          
Restructuring Cost and Reserve [Line Items]          
Area under sublease agreement     5,249ziop_SubleasedAgreementArea
/ us-gaap_StatementGeographicalAxis
= stpr_MA
   
Loss on sublease 42,000ziop_LossOnSublease
/ us-gaap_StatementGeographicalAxis
= stpr_MA
       
Remaining contractual obligation 367,000us-gaap_ContractualObligation
/ us-gaap_StatementGeographicalAxis
= stpr_MA
       
Sublease revenue from subtenant 325,000us-gaap_OperatingLeasesRentExpenseSubleaseRentals1
/ us-gaap_StatementGeographicalAxis
= stpr_MA
       
Loss on disposal of fixed assets (194,000)us-gaap_GainLossOnSaleOfPropertyPlantEquipment
/ us-gaap_StatementGeographicalAxis
= stpr_MA
       
Security deposit 20,000us-gaap_SecurityDeposit
/ us-gaap_StatementGeographicalAxis
= stpr_MA
127,000us-gaap_SecurityDeposit
/ us-gaap_StatementGeographicalAxis
= stpr_MA
  127,000us-gaap_SecurityDeposit
/ us-gaap_StatementGeographicalAxis
= stpr_MA
 
Date of sublease vacated for lease       2014-10  
Amount applied for deposit       20,000us-gaap_CustomerDepositsCurrent
/ us-gaap_StatementGeographicalAxis
= stpr_MA
 
New York, NY          
Restructuring Cost and Reserve [Line Items]          
Area under sublease agreement         7,259ziop_SubleasedAgreementArea
/ us-gaap_StatementGeographicalAxis
= stpr_NY
Loss on sublease 729,000ziop_LossOnSublease
/ us-gaap_StatementGeographicalAxis
= stpr_NY
       
Remaining contractual obligation 2,300,000us-gaap_ContractualObligation
/ us-gaap_StatementGeographicalAxis
= stpr_NY
       
Sublease revenue from subtenant 1,600,000us-gaap_OperatingLeasesRentExpenseSubleaseRentals1
/ us-gaap_StatementGeographicalAxis
= stpr_NY
       
Loss on disposal of fixed assets (392,000)us-gaap_GainLossOnSaleOfPropertyPlantEquipment
/ us-gaap_StatementGeographicalAxis
= stpr_NY
       
General and Administrative Expense          
Restructuring Cost and Reserve [Line Items]          
Restructuring charges 600,000us-gaap_RestructuringCharges
/ us-gaap_IncomeStatementLocationAxis
= us-gaap_GeneralAndAdministrativeExpenseMember
       
Research and Development Expense          
Restructuring Cost and Reserve [Line Items]          
Restructuring charges $ 1,100,000us-gaap_RestructuringCharges
/ us-gaap_IncomeStatementLocationAxis
= us-gaap_ResearchAndDevelopmentExpenseMember