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Stockholders' Equity, Stock Option (Details) - USD ($)
$ / shares in Units, $ in Thousands
3 Months Ended 12 Months Ended
Mar. 31, 2017
Dec. 31, 2017
Dec. 31, 2016
Dec. 31, 2015
Share-based Compensation, Shares Authorized under Stock Option Plans, Exercise Price Range [Line Items]        
Options outstanding, number of options (in shares)   732,190    
$2.29 - $2.29 [Member]        
Share-based Compensation, Shares Authorized under Stock Option Plans, Exercise Price Range [Line Items]        
Exercise price range, lower range limit (in dollars per share)   $ 2.29    
Exercise price range, upper range limit (in dollars per share)   $ 2.29    
Options outstanding, number of options (in shares)   428,013    
Options outstanding, weighted average remaining contractual life   9 years 9 months 29 days    
Options outstanding, weighted average exercise price (in dollars per share)   $ 2.29    
$2.51 - $2.51 [Member]        
Share-based Compensation, Shares Authorized under Stock Option Plans, Exercise Price Range [Line Items]        
Exercise price range, lower range limit (in dollars per share)   2.51    
Exercise price range, upper range limit (in dollars per share)   $ 2.51    
Options outstanding, number of options (in shares)   115,438    
Options outstanding, weighted average remaining contractual life   8 years 1 month 17 days    
Options outstanding, weighted average exercise price (in dollars per share)   $ 2.51    
$2.52 - $5.10 [Member]        
Share-based Compensation, Shares Authorized under Stock Option Plans, Exercise Price Range [Line Items]        
Exercise price range, lower range limit (in dollars per share)   2.52    
Exercise price range, upper range limit (in dollars per share)   $ 5.10    
Options outstanding, number of options (in shares)   74,784    
Options outstanding, weighted average remaining contractual life   7 years 8 months 1 day    
Options outstanding, weighted average exercise price (in dollars per share)   $ 2.84    
$6.30 - $11.73 [Member]        
Share-based Compensation, Shares Authorized under Stock Option Plans, Exercise Price Range [Line Items]        
Exercise price range, lower range limit (in dollars per share)   6.30    
Exercise price range, upper range limit (in dollars per share)   $ 11.73    
Options outstanding, number of options (in shares)   73,805    
Options outstanding, weighted average remaining contractual life   2 years 1 month 17 days    
Options outstanding, weighted average exercise price (in dollars per share)   $ 7.86    
$12.48 - $15.33 [Member]        
Share-based Compensation, Shares Authorized under Stock Option Plans, Exercise Price Range [Line Items]        
Exercise price range, lower range limit (in dollars per share)   12.48    
Exercise price range, upper range limit (in dollars per share)   $ 15.33    
Options outstanding, number of options (in shares)   9,963    
Options outstanding, weighted average remaining contractual life   3 years 3 months 4 days    
Options outstanding, weighted average exercise price (in dollars per share)   $ 13.02    
$15.51 - $18.39 [Member]        
Share-based Compensation, Shares Authorized under Stock Option Plans, Exercise Price Range [Line Items]        
Exercise price range, lower range limit (in dollars per share)   15.51    
Exercise price range, upper range limit (in dollars per share)   $ 18.39    
Options outstanding, number of options (in shares)   30,187    
Options outstanding, weighted average remaining contractual life   2 years 5 months 16 days    
Options outstanding, weighted average exercise price (in dollars per share)   $ 17.73    
Stock Options [Member]        
Outstanding options, number of shares [Roll Forward]        
Outstanding options, beginning of period (in shares) 1,381,843 1,381,843 1,223,156  
Granted (in shares)   430,500 663,431  
Exercised (in shares)   0 (185)  
Forfeited (in shares)   (1,080,153) (504,559)  
Outstanding options, end of period (in shares)   732,190 1,381,843 1,223,156
Options vested and expected to vest (in shares)   679,822    
Exercisable (in shares)   231,039    
Outstanding options, weighted average exercise price per share [Roll Forward]        
Outstanding options, beginning of period (in dollars per share) $ 14.85 $ 14.85 $ 8.22  
Granted (in dollars per share)   2.29 2.51  
Exercised (in dollars per share)   0 2.51  
Forfeited (in dollars per share)   5.90 7.12  
Outstanding options, end of period (in dollars per share)   3.72 $ 14.85 $ 8.22
Options vested and expected to vest (in dollars per share)   3.83    
Exercisable (in dollars per share)   $ 6.72    
Outstanding options, additional disclosures [Abstract]        
Outstanding options, weighted average remaining contractual term   8 years 2 months 1 day 4 years 11 months 12 days 6 years 7 months 28 days
Options vested and expected to vest, weighted average remaining contractual term   8 years 22 days    
Exercisable, weighted average remaining contractual term   5 years 1 month 24 days    
Outstanding options, aggregate intrinsic value   $ 56 $ 50 $ 0
Options vested and expected to vest, aggregate intrinsic value   50    
Exercisable, aggregate intrinsic value   3    
Options exercised in period, aggregate intrinsic value   0 0  
Fair value of options vested   32 $ 1,300  
Compensation cost not yet recognized [Abstract]        
Unrecognized compensation cost related to stock options   $ 798    
Weighted average period of recognition for unrecognized compensation cost   2 years 7 months 24 days    
Stock Options [Member] | Chief Financial Officer [Member]        
Outstanding options, number of shares [Roll Forward]        
Forfeited (in shares) (50,000)      
Compensation cost not yet recognized [Abstract]        
Reversal of previously recorded stock based compensation expense $ 58