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Acquisition - Narrative (Details)
$ / shares in Units, $ in Thousands
1 Months Ended 3 Months Ended 12 Months Ended
Aug. 04, 2021
USD ($)
$ / shares
shares
May 24, 2021
days
Aug. 31, 2023
shares
Jun. 30, 2023
USD ($)
$ / shares
shares
Jan. 31, 2023
USD ($)
$ / shares
shares
Aug. 31, 2022
shares
Aug. 31, 2021
shares
Sep. 30, 2023
shares
Sep. 30, 2022
shares
Sep. 30, 2021
shares
Dec. 31, 2023
USD ($)
Dec. 31, 2022
USD ($)
Dec. 31, 2021
USD ($)
Business Acquisition [Line Items]                          
Share price (in usd per share) | $ / shares       $ 21.10 $ 18.50                
Research and Development Asset Acquired Other than through Business Combination, Writeoff, Statement of Income or Comprehensive Income [Extensible Enumeration]                     Research and development    
Cash paid in acquisition                     $ 0 $ 0 $ 6,704
Consecutive trading day period (in days) | days   45                      
Adrestia Therapeutics Ltd                          
Business Acquisition [Line Items]                          
Shares issued in asset acquisition (in shares) | shares       3,430,867                  
Asset acquisition, consideration transferred       $ 72,400                  
Contingent payment, value       $ 326,500                  
IPR&D expense                     76,500    
Vertuis Bio, Inc.                          
Business Acquisition [Line Items]                          
Shares issued in asset acquisition (in shares) | shares         500,000                
Asset acquisition, consideration transferred                     10,250    
Contingent payment, value         $ 1,000                
IPR&D expense                     $ 10,300    
Vertuis Bio, Inc. | Milestone Event 1                          
Business Acquisition [Line Items]                          
Contingent payment, value         1,000                
Vertuis Bio, Inc. | Milestone Event 2                          
Business Acquisition [Line Items]                          
Contingent payment, value         23,000                
Vertuis Bio, Inc. | Milestone Event 3                          
Business Acquisition [Line Items]                          
Contingent payment, value         $ 63,800                
Motus Biosciences, Inc. and AlgaeneX, Inc.                          
Business Acquisition [Line Items]                          
Cash paid in acquisition $ 10,500                        
Acquisition related expenses                         $ 600
Motus Biosciences, Inc.                          
Business Acquisition [Line Items]                          
Shares issued in acquisition (in shares) | shares 2,889,367   177,203     171,427 171,427 177,203 171,427 2,889,367      
Shares issued upon milestone achievements (in shares) | shares 5,348,572           5,348,572            
Cash to be paid upon achievement of milestones $ 35,000                        
Share price used to calculate issuable shares (in dollars per share) | $ / shares $ 27.11                        
Motus Biosciences, Inc. | First anniversary of closing date                          
Business Acquisition [Line Items]                          
Shares issued in acquisition (in shares) | shares 184,433           184,433            
Motus Biosciences, Inc. | Second anniversary of closing date                          
Business Acquisition [Line Items]                          
Shares issued in acquisition (in shares) | shares 184,433           184,433            
Motus Biosciences, Inc. | Third anniversary of closing date                          
Business Acquisition [Line Items]                          
Shares issued in acquisition (in shares) | shares 184,433           184,433            
AlgaeneX, Inc.                          
Business Acquisition [Line Items]                          
Shares issued upon milestone achievements (in shares) | shares 368,867                        
Cash paid in acquisition $ 1,500                        
Share price used to calculate issuable shares (in dollars per share) | $ / shares $ 27.11