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Shareholders' Equity (Details) - USD ($)
$ / shares in Units, $ in Millions
1 Months Ended 3 Months Ended 12 Months Ended
Aug. 04, 2021
Aug. 31, 2023
Jan. 31, 2023
Aug. 31, 2022
Aug. 31, 2021
Sep. 30, 2023
Jun. 30, 2023
Dec. 31, 2022
Sep. 30, 2022
Sep. 30, 2021
Jun. 30, 2021
Mar. 31, 2021
Dec. 31, 2023
Class of Stock [Line Items]                          
Common stock, authorized shares (in shares)               500,000,000         500,000,000
Common stock, par value (in dollars per share)               $ 0.01         $ 0.01
Common stock, issued shares (in shares)               135,653,731         147,977,960
Common stock, outstanding shares (in shares)               135,653,731         147,977,960
Offering price per share (in dollars per share)               $ 20.00     $ 25.00    
Payments of stock issuance costs               $ 16.2     $ 17.5    
Preferred stock, authorized (in shares)               200,000,000         200,000,000
Preferred stock, par value (in shares)               $ 0.01         $ 0.01
Preferred stock, shares issued (in shares)               0         0
Preferred stock, shares outstanding (in shares)               0         0
Public Stock Offering                          
Class of Stock [Line Items]                          
Shares sold in offering (in shares)               13,750,000     11,500,000    
Aggregate net proceeds from stock offering               $ 258.8     $ 270.1    
Over-Allotment Option                          
Class of Stock [Line Items]                          
Shares sold in offering (in shares)                     1,500,000    
ATM Program                          
Class of Stock [Line Items]                          
Offering price per share (in dollars per share)                         $ 24.12
Aggregate net proceeds from stock offering                         $ 152.2
Common stock authorized, aggregate gross sales proceeds (up to)                       $ 250.0  
Remaining authorized amount (in shares)                         $ 58.7
Motus Biosciences, Inc.                          
Class of Stock [Line Items]                          
Common stock shares reserved for issuance (in shares)           9,406,112             9,406,112
Shares issued in acquisition (in shares) 2,889,367 177,203   171,427 171,427 177,203     171,427 2,889,367      
Contingent consideration $ 35.0                        
Shares sold in offering (in shares)                         6,503,041
Adrestia Therapeutics Ltd                          
Class of Stock [Line Items]                          
Issuance of common stock for business acquisition (in shares)             3,430,867            
Vertuis Bio, Inc.                          
Class of Stock [Line Items]                          
Common stock shares reserved for issuance (in shares)     550,000                    
Issuance of common stock for business acquisition (in shares)     500,000                    
Contingent consideration                         $ 1.0
Convertible notes                          
Class of Stock [Line Items]                          
Common stock shares reserved for issuance (in shares)                         23,438,430
Common stock options                          
Class of Stock [Line Items]                          
Common stock shares reserved for issuance (in shares)                         22,512,569
RSUs                          
Class of Stock [Line Items]                          
Common stock shares reserved for issuance (in shares)                         2,750,294
PSUs                          
Class of Stock [Line Items]                          
Common stock shares reserved for issuance (in shares)                         666,382