Summary of Significant Accounting Policies - Narrative (Details) $ in Thousands	12 Months Ended
	Dec. 31, 2023 USD ($) segment reportingUnit	Dec. 31, 2022 USD ($)	Jan. 01, 2022 USD ($)
Fair Value Measurement Inputs and Valuation Techniques [Line Items]
Number of reporting units | reportingUnit	1
Number of operating segments | segment	1
Number of reportable segments | segment	1
Debt, long-term	$ 1,155,313	$ 1,125,250
Deferred tax liabilities	(22,591)	(24,966)
Accumulated deficit	(3,446,145)	(2,696,578)
Additional paid-in capital	$ (3,113,487)	$ (2,782,416)
Cumulative Effect, Period of Adoption, Adjustment
Fair Value Measurement Inputs and Valuation Techniques [Line Items]
Debt, long-term			$ 221,900
Unamortized debt issuance costs			6,100
Deferred tax liabilities			1,400
Accumulated deficit			50,200
Additional paid-in capital			$ 264,600
Laboratory equipment, office equipment, manufacturing equipment and furniture and fixtures
Fair Value Measurement Inputs and Valuation Techniques [Line Items]
Estimated Useful Life (years)	7 years
Minimum | Computer hardware and software
Fair Value Measurement Inputs and Valuation Techniques [Line Items]
Estimated Useful Life (years)	3 years
Maximum | Computer hardware and software
Fair Value Measurement Inputs and Valuation Techniques [Line Items]
Estimated Useful Life (years)	5 years