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Summary of Significant Accounting Policies (Tables)
6 Months Ended
Jun. 30, 2023
Accounting Policies [Abstract]  
Schedule of Percentage of Total Gross Product Revenue Represented by the Three Largest Customers The following table presents the percentage of gross product revenue represented by the Company's three largest customers as of the six months ended June 30, 2023 and their respective percentages for the six months ended June 30, 2022.
June 30,
20232022
Customer A36%36%
Customer B35%32%
Customer C17%19%
Reconciliation of the Weighted Average Number of Shares Used to Compute Basic and Diluted Net Loss per Share
The following table sets forth the reconciliation of the weighted average number of common shares used to compute basic and diluted net loss per share for the three and six months ended June 30, 2023 and 2022:
 Three Months Ended June 30, 2022Six Months Ended June 30,
 2023202220232022
 
Numerator:  
Net loss$(244,809)$(95,645)$(404,573)$(190,266)
Denominator:  
Weighted average common shares used in calculation of basic net loss per share:137,553 119,602 136,957 119,267 
Effect of dilutive securities:  
Common stock options— — — — 
RS and RSUs— — — — 
PSUs— — — — 
Convertible debt securities— — — — 
Weighted average common shares outstanding used in calculation of diluted net loss per share137,553 119,602 136,957 119,267 
Net loss per share:  
Basic and diluted$(1.78)$(0.80)$(2.95)$(1.60)
Potentially Dilutive Securities Excluded from Computations of Diluted Weighted Average Common Shares Outstanding
The following potentially dilutive securities have been excluded from the computations of diluted weighted average common shares outstanding as of June 30, 2023 and 2022, respectively, as their effect would have been anti-dilutive (in thousands):
 
June 30,
 20232022
Common stock options21,999 17,806 
Unvested restricted stock and RSUs2,828 1,619 
PSUs666 670 
Convertible debt securities23,438 23,438