Amount of accumulated depreciation, depletion and amortization for physical assets used in the normal conduct of business to produce goods and services.

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The aggregate expense recognized in the current period that allocates the cost of tangible assets, intangible assets, or depleting assets to periods that benefit from use of the assets.

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Amount before accumulated depreciation, depletion and amortization of physical assets used in the normal conduct of business and not intended for resale. Examples include, but are not limited to, land, buildings, machinery and equipment, office equipment, and furniture and fixtures.

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Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.

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Amount after accumulated depreciation, depletion and amortization of physical assets used in the normal conduct of business to produce goods and services and not intended for resale. Examples include, but are not limited to, land, buildings, machinery and equipment, office equipment, and furniture and fixtures.

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Useful life of long lived, physical assets used in the normal conduct of business and not intended for resale, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents the reported fact of one year, five months, and thirteen days. Examples include, but not limited to, land, buildings, machinery and equipment, office equipment, furniture and fixtures, and computer equipment.

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Fixed Assets, net (Details) - USD ($) $ in Thousands	12 Months Ended
Fixed Assets, net (Details) - USD ($) $ in Thousands	Dec. 31, 2021	Dec. 31, 2020	Dec. 31, 2019
Property, Plant and Equipment
Fixed assets, gross	$ 90,016	$ 82,303
Less accumulated depreciation	(37,061)	(28,350)
Fixed assets, net	52,955	53,953
Depreciation expense	$ 9,100	9,100	$ 5,200
Lab equipment
Property, Plant and Equipment
Estimated Useful Life (years)	7 years
Fixed assets, gross	$ 11,862	10,352
Furniture and fixtures
Property, Plant and Equipment
Estimated Useful Life (years)	7 years
Fixed assets, gross	$ 5,799	5,917
Computer hardware and software
Property, Plant and Equipment
Fixed assets, gross	$ 7,264	7,267
Computer hardware and software \| Minimum
Property, Plant and Equipment
Estimated Useful Life (years)	3 years
Computer hardware and software \| Maximum
Property, Plant and Equipment
Estimated Useful Life (years)	5 years
Office equipment
Property, Plant and Equipment
Estimated Useful Life (years)	7 years
Fixed assets, gross	$ 89	88
Manufacturing equipment
Property, Plant and Equipment
Estimated Useful Life (years)	7 years
Fixed assets, gross	$ 1,145	1,567
Leasehold improvements
Property, Plant and Equipment
Fixed assets, gross	36,073	35,289
Construction in progress (CIP)
Property, Plant and Equipment
Fixed assets, gross	$ 27,784	$ 21,823