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Summary of Significant Accounting Policies - Anti-dilutive Securities (Details) - shares
shares in Thousands
9 Months Ended
Sep. 30, 2021
Sep. 30, 2020
Common stock options    
Anti-dilutive securities excluded from computations of diluted weighted-average common shares outstanding    
Potentially dilutive securities excluded from computations of diluted weighted-average shares outstanding (in shares) 14,518 13,047
Unvested restricted stock and RSUs    
Anti-dilutive securities excluded from computations of diluted weighted-average common shares outstanding    
Potentially dilutive securities excluded from computations of diluted weighted-average shares outstanding (in shares) 1,069 853
Convertible debt securities    
Anti-dilutive securities excluded from computations of diluted weighted-average common shares outstanding    
Potentially dilutive securities excluded from computations of diluted weighted-average shares outstanding (in shares) 23,438 11,492