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License and Other Agreements (Details)
€ in Millions, $ in Millions
1 Months Ended 12 Months Ended
Oct. 31, 2016
USD ($)
Jul. 31, 2014
Feb. 28, 2014
USD ($)
Apr. 30, 2008
EUR (€)
Dec. 31, 2019
USD ($)
Dec. 31, 2016
USD ($)
Dec. 31, 2009
USD ($)
Dec. 31, 2004
USD ($)
Oct. 31, 2017
USD ($)
Sep. 30, 2015
USD ($)
PARI Agreement                    
Collaboration Agreements                    
Initial term of contract manufacturing agreement   15 years                
Additional term of contract manufacturing agreement   5 years                
PARI Agreement | Maximum                    
Collaboration Agreements                    
Future milestone payments | €       € 0.5            
PARI Agreement | Minimum                    
Collaboration Agreements                    
Written notice period required for termination of contract manufacturing agreement   1 year                
CFFT                    
Collaboration Agreements                    
Compensation earned under research funding agreements with CFFT             $ 2.2 $ 1.7    
Royalty payable on approval of ARIKAYCE as commercialized drug         $ 13.4          
Period for meeting sales milestones for additional royalty payments         5 years          
Royalty payable on meeting certain sales milestones         $ 3.9          
Therapure                    
Collaboration Agreements                    
Initial term of contract manufacturing agreement     5 years              
Period of each automatic renewal of contract manufacturing agreement     2 years              
Written notice period required for termination of contract manufacturing agreement     2 years              
Minimum obligation     $ 6.0              
Fill/Finish Agreement                    
Collaboration Agreements                    
Minimum obligation                   $ 2.7
Period prior to expiration for extension         1 year          
License Agreement with AstraZeneca                    
Collaboration Agreements                    
Royalty payment $ 35.0                  
License Agreement with AstraZeneca | Research and development expenses                    
Collaboration Agreements                    
Upfront payment           $ 30.0        
License Agreement with AstraZeneca | Maximum                    
Collaboration Agreements                    
Aggregate payment upon the achievement of certain clinical milestones 85.0                  
Additional contingent payments upon second indication to develop INS1007 42.5                  
Supply Agreement with Patheon UK Limited                    
Collaboration Agreements                    
Agreement to purchase raw materials and fixed assets                 $ 60.0  
License and Service | License Agreement with AstraZeneca                    
Collaboration Agreements                    
Annual net sales $ 1,000.0                  
Milestone, New Drug Application | PARI Agreement                    
Collaboration Agreements                    
PARI milestone upon FDA approval | €       1.0            
Milestone, FDA Approval | PARI Agreement                    
Collaboration Agreements                    
PARI milestone upon FDA approval | €       € 1.5