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Stock-Based Compensation (Details 2) (USD $)
12 Months Ended 3 Months Ended
Dec. 31, 2014
Dec. 31, 2013
Dec. 31, 2012
Mar. 31, 2015
Stock Option disclosures        
Granted (in shares) 1,600,452us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGross 2,323,500us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGross 1,116,384us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGross  
Number of Shares        
Options outstanding (in shares) 3,632,996us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber 1,817,839us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber 891,751us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber  
Granted (in shares) 1,600,452us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGross 2,323,500us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGross 1,116,384us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGross  
Exercised (in shares) (283,057)us-gaap_StockIssuedDuringPeriodSharesStockOptionsExercised (371,743)us-gaap_StockIssuedDuringPeriodSharesStockOptionsExercised (30,250)us-gaap_StockIssuedDuringPeriodSharesStockOptionsExercised  
Forfeited or expired (in shares) (550,285)us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsForfeituresAndExpirationsInPeriod (136,600)us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsForfeituresAndExpirationsInPeriod (160,046)us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsForfeituresAndExpirationsInPeriod  
Options outstanding (in shares) 4,400,106us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber 3,632,996us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber 1,817,839us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber  
Vested and expected to vest (in shares) 3,891,511us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingNumber 3,402,306us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingNumber 1,692,915us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingNumber  
Exercisable (in shares) 1,235,710us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableNumber 484,213us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableNumber 438,145us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableNumber  
Weighted Average Exercise Price        
Options outstanding (in dollars per share) $ 7.94us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice $ 4.10us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice $ 5.15us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice  
Granted (in dollars per share) $ 16.10us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageExercisePrice $ 10.53us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageExercisePrice $ 4.12us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageExercisePrice  
Exercised (in dollars per share) $ 6.11us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExercisesInPeriodWeightedAverageExercisePrice $ 4.37us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExercisesInPeriodWeightedAverageExercisePrice $ 7.08us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExercisesInPeriodWeightedAverageExercisePrice  
Forfeited or expired (in dollars per share) $ 11.42us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsForfeituresAndExpirationsInPeriodWeightedAverageExercisePrice $ 10.49us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsForfeituresAndExpirationsInPeriodWeightedAverageExercisePrice $ 9.54us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsForfeituresAndExpirationsInPeriodWeightedAverageExercisePrice  
Options outstanding (in dollars per share) $ 10.59us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice $ 7.94us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice $ 4.10us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice  
Vested and expected to vest (in dollars per share) $ 10.32us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingWeightedAverageExercisePrice $ 7.88us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingWeightedAverageExercisePrice $ 4.11us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingWeightedAverageExercisePrice  
Exercisable (in dollars per share) $ 6.90us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableWeightedAverageExercisePrice $ 4.25us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableWeightedAverageExercisePrice $ 4.59us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableWeightedAverageExercisePrice  
Weighted Average Remaining Contractual Life        
Options outstanding 8 years 5 months 19 days      
Vested and expected to vest 8 years 5 months 5 days      
Exercisable 7 years 11 months 9 days      
Aggregate Intrinsic Value        
Options outstanding (in dollars) $ 24,172,000us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValue      
Vested and expected to vest (in dollars) 22,304,000us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingAggregateIntrinsicValue      
Exercisable (in dollars) 10,597,000us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsExercisableIntrinsicValue1      
Stock options        
Fair value and assumptions used in determining fair value of stock options        
Dividend yield (as a percent) 0.00%us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedDividendRate
/ us-gaap_AwardTypeAxis
= insm_EmployeeAndDirectorsStockOptionsMember
0.00%us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedDividendRate
/ us-gaap_AwardTypeAxis
= insm_EmployeeAndDirectorsStockOptionsMember
0.00%us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedDividendRate
/ us-gaap_AwardTypeAxis
= insm_EmployeeAndDirectorsStockOptionsMember
 
Expected option term 6 years 3 months 6 years 3 months 6 years 3 months  
Weighted-average fair value of stock options granted (in dollars per share) $ 11.74us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageGrantDateFairValue
/ us-gaap_AwardTypeAxis
= insm_EmployeeAndDirectorsStockOptionsMember
$ 8.16us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageGrantDateFairValue
/ us-gaap_AwardTypeAxis
= insm_EmployeeAndDirectorsStockOptionsMember
$ 3.21us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageGrantDateFairValue
/ us-gaap_AwardTypeAxis
= insm_EmployeeAndDirectorsStockOptionsMember
 
Stock options | Minimum        
Fair value and assumptions used in determining fair value of stock options        
Volatility (as a percent) 83.00%us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRate
/ us-gaap_AwardTypeAxis
= insm_EmployeeAndDirectorsStockOptionsMember
/ us-gaap_RangeAxis
= us-gaap_MinimumMember
86.00%us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRate
/ us-gaap_AwardTypeAxis
= insm_EmployeeAndDirectorsStockOptionsMember
/ us-gaap_RangeAxis
= us-gaap_MinimumMember
99.00%us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRate
/ us-gaap_AwardTypeAxis
= insm_EmployeeAndDirectorsStockOptionsMember
/ us-gaap_RangeAxis
= us-gaap_MinimumMember
 
Risk-free interest rate (as a percent) 1.46%us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRate
/ us-gaap_AwardTypeAxis
= insm_EmployeeAndDirectorsStockOptionsMember
/ us-gaap_RangeAxis
= us-gaap_MinimumMember
0.65%us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRate
/ us-gaap_AwardTypeAxis
= insm_EmployeeAndDirectorsStockOptionsMember
/ us-gaap_RangeAxis
= us-gaap_MinimumMember
0.57%us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRate
/ us-gaap_AwardTypeAxis
= insm_EmployeeAndDirectorsStockOptionsMember
/ us-gaap_RangeAxis
= us-gaap_MinimumMember
 
Stock options | Maximum        
Fair value and assumptions used in determining fair value of stock options        
Volatility (as a percent) 86.00%us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRate
/ us-gaap_AwardTypeAxis
= insm_EmployeeAndDirectorsStockOptionsMember
/ us-gaap_RangeAxis
= us-gaap_MaximumMember
96.00%us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRate
/ us-gaap_AwardTypeAxis
= insm_EmployeeAndDirectorsStockOptionsMember
/ us-gaap_RangeAxis
= us-gaap_MaximumMember
107.00%us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRate
/ us-gaap_AwardTypeAxis
= insm_EmployeeAndDirectorsStockOptionsMember
/ us-gaap_RangeAxis
= us-gaap_MaximumMember
 
Risk-free interest rate (as a percent) 1.83%us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRate
/ us-gaap_AwardTypeAxis
= insm_EmployeeAndDirectorsStockOptionsMember
/ us-gaap_RangeAxis
= us-gaap_MaximumMember
1.65%us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRate
/ us-gaap_AwardTypeAxis
= insm_EmployeeAndDirectorsStockOptionsMember
/ us-gaap_RangeAxis
= us-gaap_MaximumMember
0.99%us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRate
/ us-gaap_AwardTypeAxis
= insm_EmployeeAndDirectorsStockOptionsMember
/ us-gaap_RangeAxis
= us-gaap_MaximumMember
 
Performance shares        
Number of Shares        
Options outstanding (in shares) 396,667us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber
/ us-gaap_AwardTypeAxis
= us-gaap_PerformanceSharesMember
     
Performance shares | Forecast        
Aggregate Intrinsic Value        
Performance options expense       $ 1,500,000us-gaap_StockOptionPlanExpense
/ us-gaap_AwardTypeAxis
= us-gaap_PerformanceSharesMember
/ us-gaap_StatementScenarioAxis
= us-gaap_ScenarioForecastMember