UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

FORM 8-K

CURRENT REPORT

Pursuant to Section 13 or Section 15(d) of the Securities Exchange Act of 1934

Date of Report (Date of earliest event reported) June 22, 2007

BioDelivery Sciences International, Inc.

(Exact name of registrant as specified in its charter)

Delaware	0-28931	35-2089858
(State or other jurisdiction of incorporation)	(Commission File Number)	(IRS Employer Identification No.)

2501 Aerial Center Parkway, Suite 205 Morrisville, North Carolina	27560
(Address of principal executive offices)	(Zip Code)

Registrant’s telephone number, including area code: (919) 653-5160

Not Applicable

(Former name or former address, if changed since last report)

Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation to the registrant under any of the following provisions:

¨ Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)

¨ Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)

¨ Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))

¨ Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))

Items 7.01 and 8.01. Regulation FD Disclosure and Other Information.

(a) On June 22, 2007, BioDelivery Sciences International, Inc. (the “Company”) delivered formal notice to the Boston Stock Exchange (“BSE”) of its intention to voluntarily withdraw the Company’s publicly-traded securities from the BSE. The Company also issued a press release relating to this development. The press release is attached to this Current Report on Form 8-K as Exhibit 99.1.

(b) On June 22, 2007, the Company, in the same press release referred to above, reiterated, as previously announced, that its publicly-traded warrants are set to expire on Monday, June 25, 2007. Investors wishing to exercise their warrants must deliver all appropriate documentation and funds to the Company c/o James A. McNulty, CFO, 324 South Hyde Park Avenue, Suite 350, Tampa FL 33606, (813) 864-2562, by 5:00 p.m Eastern time on Monday, June 25, 2007. As a result of this expiration, BDSI will formally delist such warrants in the near future.

Item 9.01. Financial Statements and Exhibits.

(d) Exhibits

99.1 Press release, dated June 22, 2007, regarding voluntary withdrawal from Boston Stock Exchange.

This Current Report on Form 8-K and the exhibits hereto may contain, among other things, certain forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995, including, without limitation, statements with respect to the Company’s plans, objectives, expectations and intentions and other statements identified by words such as “may”, “could”, “would”, “should”, “believes”, “expects”, “anticipates”, “estimates”, “intends”, “plans” or similar expressions. These statements are based upon the current beliefs and expectations of the Company’s management and are subject to significant risks and uncertainties. Actual results may differ from those set forth in the forward-looking statements. These forward-looking statements involve certain risks and uncertainties that are subject to change based on various factors (many of which are beyond the Company’s control).

SIGNATURES

Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has caused this report to be signed on its behalf by the undersigned hereunto duly authorized.

June 22, 2007	BIODELIVERY SCIENCES INTERNATIONAL, INC.
	By:	/s/ James A. McNulty
	Name:	James A. McNulty
	Title:	Secretary, Treasurer and Chief Financial Officer