8-K

UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

WASHINGTON, D.C. 20549

FORM 8-K

CURRENT REPORT

Pursuant to Section 13 OR 15 (d) of the

Securities Exchange Act of 1934

May 8, 2007

Date of Report (Date of earliest event reported)

CHARLES RIVER LABORATORIES INTERNATIONAL, INC.

(Exact Name of Registrant as specified in its Charter)

Delaware	333-92383	06-1397316
(State or Other Jurisdiction of Incorporation)	(Commission File Number)	(I.R.S. Employer  Identification No.)

251 Ballardvale Street

Wilmington, Massachusetts 01887

(Address of Principal Executive Offices) (Zip Code)

978-658-6000

(Registrant's Telephone Number, including Area Code)

Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions:

|_| Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)

|_| Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)

|_| Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))

|_| Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))

ITEM 2.02. Results of Operations and Financial Condition

The following information shall not be deemed "filed" for purposes of Section 18 of the Securities Exchange Act of 1934, as amended (the "Exchange Act"), or incorporated by reference in any filing under the Securities Act of 1933, as amended, or the Exchange Act, except as shall be expressly set forth by specific reference in such a filing.

On May 8, 2007, Charles River Laboratories International, Inc. issued a press release providing financial results for the quarter ended March 31, 2007.

The press release, attached as an exhibit to this report, includes "safe harbor" language pursuant to the Private Securities Litigation Reform Act of 1995, as amended, indicating that certain statements contained in the press release are "forward-looking" rather than historic. The press release also states that these and other risks relating to Charles River are set forth in the documents filed by Charles River with the Securities and Exchange Commission.

ITEM 9.01.	Financial Statements and Exhibits
(a)	Not applicable.
(b)	Not applicable.
(c)	Exhibits.

99.1 Press release dated May 8, 2007.

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SIGNATURES

Pursuant to the requirements of the Securities Exchange Act of 1934, as amended, we have duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.

	CHARLES RIVER LABORATORIES INTERNATIONAL, INC.
Date: May 8, 2007	By:	/s/ Joanne P. Acford
		Joanne P. Acford, Corporate Senior Vice
		President, General Counsel and Corporate Secretary

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Exhibit Index

Exhibit No.	Description
99.1	Press release dated May 8, 2007.

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EX-99.1

NEWS RELEASE

CHARLES RIVER LABORATORIES ANNOUNCES FIRST-QUARTER 2007 RESULTS FROM CONTINUING OPERATIONS

- First-Quarter Sales Increase 14.6% to $291 Million -

- First-Quarter GAAP EPS Increase 41% to $0.55 -

- First-Quarter Non-GAAP EPS Increase 33.3% to $0.64 -

- Reaffirms Guidance for 2007 -

WILMINGTON, MA, May 8, 2007, (Businesswire) - Charles River Laboratories International, Inc. (NYSE: CRL) today reported first-quarter 2007 financial results. For the first quarter, net sales from continuing operations increased 14.6% to $291.2 million from $254.1 million in the first quarter of 2006. Strong sales growth in both the Research Models and Services and Preclinical Services business segments drove the increase, as pharmaceutical and biotechnology customers increased their purchases of research models and continued to outsource services. Foreign exchange contributed 2.7% to the net sales growth.

On a GAAP basis, net income from continuing operations for the first quarter of 2007 was $37.2 million, or $0.55 per diluted share, compared to $28.5 million, or $0.39 per diluted share, for the first quarter of 2006. The 40.7% increase in earnings per share resulted primarily from higher sales, as well as the benefit of cost savings initiatives implemented in 2006, a lower share count due to the Company’s stock repurchase program, lower amortization of intangible assets and reduced net interest expense.

On a non-GAAP basis, net income from continuing operations was $43.2 million for the first quarter of 2007, compared to $34.8 million for the same period in 2006.First-quarter diluted earnings per share on a non-GAAP basis were $0.64, compared to $0.48 per share in the first quarter of 2006. Non-GAAP earnings per share in the first quarter of 2007 excluded $7.9 million of amortization of intangible assets and stock-based compensation related to acquisitions and a charge of $0.8 million related to the decision to accelerate the exit of the Company’s Preclinical Services facility in Worcester, Massachusetts. The Company now expects to complete the transition to the new Shrewsbury, Massachusetts, facility by the end of 2007, and as a result, expects to record total related charges in 2007 of approximately $0.03 to $0.05, including the first-quarter charge.

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James C. Foster, Chairman, President and Chief Executive Officer, said, “We were very pleased by the strong start to this year. The actions we took last year to focus on our core businesses and improve our operating efficiency are reflected in our stronger sales and earnings growth. The continuing robust demand for our products and services confirms our confidence in the outlook for the year, and we are reaffirming our sales and earnings guidance for 2007.”

The Company reports results from continuing operations, which exclude results of the Interventional and Surgical Services (ISS) business. The Company is in the process of closing that business and as a result, reports it as discontinued operations. Historical comparisons have been reclassified accordingly. The net loss from discontinued operations was $0.5 million in the first quarter of 2007. Including discontinued operations, net income for the first quarter of 2007 was $36.8 million, or $0.54 per diluted share, compared to a consolidated net loss of $100.1 million, or $1.37 per diluted share, in the first quarter of 2006. Discontinued operations in 2006 included both ISS and the Phase II - IV clinical services business, which the Company sold in August 2006.

Research Models and Services (RMS)

Sales for the RMS segment were $143.1 million in the first quarter of 2007, an increase of 10.9% from $129.0 million in the first quarter of 2006. Sales benefited from strong demand for research models from large pharmaceutical customers in North America, increased demand for Transgenic Services, and higher sales of in vitro products. As expected, sales of large research models increased significantly as shipments which had been delayed from the fourth quarter of 2006 due to an extended quarantine were released.

In the first quarter of 2007, the RMS segment’s GAAP operating margin increased to 32.9% from 31.4%, primarily due to increased Transgenic Services revenue and large research model sales. On a non-GAAP basis, which excluded charges of $0.4 million for acquisition-related amortization, the operating margin was 33.1%, compared to 31.4% for the same period in the prior year.

Preclinical Services (PCS)

First-quarter net sales for the PCS segment were $148.1 million, an increase of 18.3% from $125.2 million in the first quarter of 2006. Sales were driven by continuing strong demand for general and specialty toxicology services by pharmaceutical and biotechnology customers, and the addition on October 30, 2006, of the Northwest Kinetics Phase I clinical services business.

The PCS segment’s GAAP operating margin improved to 15.8% from 11.0%, as a result of higher sales, improved operating efficiencies and lower amortization of intangible assets related to acquisitions. On a non-GAAP basis, which excludes $7.5 million of acquisition-related amortization and the $0.8 million charge for the accelerated exit from the Worcester facility, the first-quarter operating margin improved to 21.4% compared to 18.2% for the first quarter of 2006.

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2007 Guidance

The Company reaffirms its forward-looking guidance based on continuing operations for 2007, which was originally provided on December 13, 2006. This forward-looking guidance is based on current foreign exchange rates. In addition to a net charge in a range of $0.03 - $0.05 per diluted share as a result of the accelerated exit from the Worcester facility, the Company expects to report a one-time gain of approximately $0.02 per diluted share on the sale of real estate in Scotland. Both of these items will be reported as non-GAAP adjustments.

2007 GUIDANCE (from continuing operations)
Net sales growth (in %)	9% - 12%
Sales ($ in millions)	$1,160 - $1,190
GAAP EPS estimate	$2.11 - $2.21
Acquisition-related amortization	$0.32
Charge to exit Worcester facility and gain on sale of building, net	$0.01 - $0.03
Non-GAAP EPS estimate	$2.43 - $2.53

Webcast

Charles River Laboratories has scheduled a live webcast on Wednesday, May 9, at 8:30 a.m. ET to discuss matters relating to this press release. To participate, please go to ir.criver.com and select the webcast link. You can also find the associated slide presentation and reconciliations to comparable GAAP measures on the website.

Charles River to Present at Baird Conference

James C. Foster will present at the Robert W. Baird Growth Stock Conference on Thursday, May 10, at 9:30 a.m. CT, in Chicago, Illinois. Mr. Foster will present an overview of Charles River’s business and strategic focus. A live webcast of the presentation will be available through a link that will be posted on the Investor Relations section of the Charles River Laboratories website at ir.criver.com.  A webcast replay will be accessible through the same website approximately three hours after the presentation.

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Use of Non-GAAP Financial Measures

This press release contains non-GAAP financial measures, such as non-GAAP earnings per diluted share from continuing operations, which exclude amortization of intangible assets and other charges related to our acquisitions, impairments due to our accelerated exit from our Worcester Preclinical Services facility, and the potential gain on the sale of real estate in Scotland. We exclude these items from the non-GAAP financial measures because they are outside our normal operations. There are limitations in using non-GAAP financial measures, as they are not prepared in accordance with generally accepted accounting principles, and may be different than non-GAAP financial measures used by other companies. In particular, we believe that the inclusion of supplementary non-GAAP financial measures in this press release helps investors to gain a meaningful understanding of our core operating results and future prospects without the effect of one-time charges, and is consistent with how management measures and forecasts the Company's performance, especially when comparing such results to prior periods or forecasts. We believe that the financial impact of our acquisitions is often large relative to our overall financial performance, which can adversely affect the comparability of our results on a period-to-period basis. In addition, certain activities, such as business acquisitions, happen infrequently and the underlying costs associated with such activities do not recur. Non-GAAP results also allow investors to compare the Company’s operations against the financial results of other companies in the industry who similarly provide non-GAAP results. The non-GAAP financial measures included in this press release are not meant to be considered superior to or a substitute for results of operations prepared in accordance with GAAP. The Company intends to continue to assess the potential value of reporting non-GAAP results consistent with applicable rules and regulations. Reconciliations of the non-GAAP financial measures used in this press release to the most directly comparable GAAP financial measures are set forth in the text of this press release, and can also be found on the Company’s website at ir.criver.com.

Caution Concerning Forward-Looking Statements

This news release includes forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. Forward-looking statements may be identified by the use of words such as “anticipate,” “believe,” “expect,” “will,” “may,” “estimate,” “plan,” “outlook,” and “project” and other similar expressions that predict or indicate future events or trends or that are not statements of historical matters. These statements also include statements regarding our projected 2007 earnings; the future demand for drug discovery and development products and services, including the outsourcing of these services; the impact of specific actions intended to improve overall operating efficiencies and profitability; expectations regarding stock repurchases; the timing of the opening of new and expanded facilities; the potential sale of real estate in Scotland; future cost reduction activities by our customers; and Charles River’s future performance as delineated in our forward-looking guidance, and particularly our expectations with respect to sales growth. Forward-looking statements are based on Charles River’s current expectations and beliefs, and involve a number of risks and uncertainties that are difficult to predict and that could cause actual results to differ materially from those stated or implied by the forward-looking statements. Those risks and uncertainties include, but are not limited to: a decrease in research and development spending, a decrease in the level of outsourced services, or other cost reduction actions by our customers; the ability to convert backlog to sales; special interest groups; contaminations; industry trends; new displacement technologies; USDA and FDA regulations; changes in law; continued availability of products and supplies; loss of key personnel; interest rate and foreign currency exchange rate fluctuations; changes in tax regulation and laws; changes in generally accepted accounting principles; and any changes in business, political, or economic conditions due to the threat of future terrorist activity in the U.S. and other parts of the world, and related U.S. military action overseas. A further description of these risks, uncertainties, and other matters can be found in the Risk Factors detailed in Charles River's Annual Report on Form 10-K as filed on February 27, 2007, as well as other filings we make with the Securities and Exchange Commission. Because forward-looking statements involve risks and uncertainties, actual results and events may differ materially from results and events currently expected by Charles River, and Charles River assumes no obligation and expressly disclaims any duty to update information contained in this news release except as required by law.

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About Charles River Laboratories

Charles River Laboratories based in Wilmington, Massachusetts, partners with global pharmaceutical and biotechnology companies, government agencies and leading academic institutions to advance the drug discovery and development process, bringing drugs to market faster and more efficiently. Charles River's 8,000 employees serve clients worldwide. For more information on Charles River, visit our website at www.criver.com.

# # #

Investor Contact:

Susan E. Hardy

Corporate Vice President, Investor Relations

781.262.7616

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CHARLES RIVER LABORATORIES INTERNATIONAL, INC.
CONDENSED CONSOLIDATED STATEMENTS OF INCOME (UNAUDITED)
(dollars in thousands, except for per share data)
	Three Months Ended
	March 31, 2007			April 1, 2006
Total net sales	$	291,199		$	254,141
Cost of products sold and services provided		175,626			158,636
Gross margin		115,573			95,505
Selling, general and administrative		53,017			42,734
Amortization of intangibles		7,855			9,075
Operating income		54,701			43,696
Interest income (expense)		(2,059	)		(3,016	)
Other income (expense)		149			48
Income before income taxes and minority interests		52,791			40,728
Provision for income taxes		15,310			11,811
Income before minority interests		37,481			28,917
Minority interests		(254	)		(402	)
Income from continuing operations		37,227			28,515
Income (loss) from discontinued businesses, net of tax		(464	)		(128,630	)
Net income (loss)	$	36,763		$	(100,115	)
Earnings (loss) per common share
Basic:
Continuing operations	$	0.56		$	0.40
Discontinued operations	$	(0.01	)	$	(1.80	)
Net income	$	0.55		$	(1.40	)
Diluted:
Continuing operations	$	0.55		$	0.39
Discontinued operations	$	(0.01	)	$	(1.76	)
Net income	$	0.54		$	(1.37	)
Weighted average number of common shares outstanding
Basic		66,346,152			71,505,478
Diluted		67,632,780			72,890,237

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CHARLES RIVER LABORATORIES INTERNATIONAL, INC.
CONDENSED CONSOLIDATED BALANCE SHEETS (UNAUDITED)
(dollars in thousands)
	March 31, 2007		December 30, 2006
Assets
Current assets
Cash and cash equivalents	$	136,537	$	175,380
Trade receivables, net		210,166		202,658
Inventories		75,681		72,362
Other current assets		54,186		44,363
Current assets of discontinued businesses		5,669		6,330
Total current assets		482,239		501,093
Property, plant and equipment, net		566,145		534,745
Goodwill, net		1,119,389		1,119,309
Other intangibles, net		159,368		160,204
Deferred tax asset		98,599		107,498
Other assets		142,320		133,944
Long-term assets of discontinued businesses		334		751
Total assets	$	2,568,394	$	2,557,544
Liabilities and Shareholders’ Equity
Current liabilities
Current portion of long-term debt	$	25,759	$	24,977
Accounts payable		37,256		28,223
Accrued compensation		29,992		41,651
Deferred income		88,526		93,197
Accrued liabilities		43,986		41,991
Other current liabilities		20,322		25,625
Current liabilities of discontinued businesses		449		3,667
Total current liabilities		246,290		259,331
Long-term debt		527,555		547,084
Other long-term liabilities		149,911		146,695
Total liabilities		923,756		953,110
Minority interests		2,420		9,223
Total shareholders’ equity		1,642,218		1,595,211
Total liabilities and shareholders’ equity	$	2,568,394	$	2,557,544

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CHARLES RIVER LABORATORIES INTERNATIONAL, INC.
SELECTED BUSINESS SEGMENT INFORMATION (UNAUDITED)
(dollars in thousands)
	Three Months Ended
	March 31, 2007			April 1, 2006
Research Models and Services
Net sales	$	143,068		$	128,972
Gross margin		63,654			55,866
Gross margin as a % of net sales		44.5	%		43.3	%
Operating income		47,021			40,476
Operating income as a % of net sales		32.9	%		31.4	%
Depreciation and amortization		5,569			5,035
Capital expenditures		7,084			3,566
Preclinical Services
Net sales	$	148,131		$	125,169
Gross margin		51,919			39,639
Gross margin as a % of net sales		35.0	%		31.7	%
Operating income		23,444			13,788
Operating income as a % of net sales		15.8	%		11.0	%
Depreciation and amortization		14,344			14,624
Capital expenditures		30,840			35,821
Unallocated Corporate Overhead	$	(15,764	)	$	(10,568	)
Total
Net sales	$	291,199		$	254,141
Gross margin		115,573			95,505
Gross margin as a % of net sales		39.7	%		37.6	%
Operating income (loss)		54,701			43,696
Operating income as a % of net sales		18.8	%		17.2	%
Depreciation and amortization		19,913			19,659
Capital expenditures		37,924			39,387

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CHARLES RIVER LABORATORIES INTERNATIONAL, INC.
RECONCILIATION OF GAAP TO NON-GAAP
SELECTED BUSINESS SEGMENT INFORMATION (UNAUDITED)
(dollars in thousands)
	Three Months Ended
	March 31, 2007			April 1, 2006
Research Models and Services
Net sales	$	143,068		$	128,972
Operating income		47,021			40,476
Operating income as a % of net sales		32.9	%		31.4	%
Add back:
Amortization related to acquisitions		374			83
Operating income, excluding specified charges (Non-GAAP)	$	47,395		$	40,559
Non-GAAP operating income as a % of net sales		33.1	%		31.4	%
Preclinical Services
Net sales	$	148,131		$	125,169
Operating income		23,444			13,788
Operating income as a % of net sales		15.8	%		11.0	%
Add back:
Amortization related to acquisitions		7,483			8,995
Impairment and other charges		819			-
Operating income, excluding specified charges (Non-GAAP)	$	31,746		$	22,783
Non-GAAP operating income as a % of net sales		21.4	%		18.2	%
Unallocated Corporate Overhead	$	(15,764	)	$	(10,568	)
Add back:
Stock-based compensation related to Inveresk acquisition		70			285
Unallocated corporate overhead, excluding specified charges (Non-GAAP)	$	(15,694	)	$	(10,283	)
Total
Net sales	$	291,199		$	254,141
Operating income		54,701			43,696
Operating income as a % of net sales		18.8	%		17.2	%
Add back:
Amortization related to acquisitions		7,857			9,078
Impairment and other charges		819			-
Stock-based compensation related to Inveresk acquisition		70			285
Operating income, excluding specified charges (Non-GAAP)	$	63,447		$	53,059
Non-GAAP operating income as a % of net sales		21.8	%		20.9	%

Charles River management believes that supplementary non-GAAP financial measures provide useful information to allow investors to gain a meaningful understanding of our core operating results and future prospects, without the effect of one-time charges, consistent with the manner in which management measures and forecasts the Company’s performance. The supplementary non-GAAP financial measures included are not meant to be considered superior to, or a substitute for results of operations prepared in accordance with GAAP. The Company intends to continue to assess the potential value of reporting non-GAAP results consistent with applicable rules and regulations.

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CHARLES RIVER LABORATORIES INTERNATIONAL, INC.
RECONCILIATION OF GAAP EARNINGS TO NON-GAAP EARNINGS
(dollars in thousands, except for per share data)
	Three Months Ended
	March 31, 2007			April 1, 2006
Net income (loss)	$	36,763		$	(100,115	)
Less: Discontinued operations		464			128,630
Net income from continuing operations		37,227			28,515
Add back:
Amortization related to acquisitions		7,857			9,078
Stock-based compensation related to Inveresk acquisition		70			285
Impairment and other charges		819			-
Tax effect		(2,784	)		(3,066	)
Net income from continuing operations, excluding specified charges (Non-GAAP)	$	43,189		$	34,812
Weighted average shares outstanding - Basic		66,346,152			71,505,478
Effect of dilutive securities:
Stock options and contingently issued restricted stock		1,153,912			1,239,254
Warrants		132,716			145,505
Weighted average shares outstanding - Diluted		67,632,780			72,890,237
Basic earnings (loss) per share	$	0.55		$	(1.40	)
Diluted earnings (loss) per share	$	0.54		$	(1.37	)
Basic earnings per share, excluding specified charges (Non-GAAP)	$	0.65		$	0.49
Diluted earnings per share, excluding specified charges (Non-GAAP)	$	0.64		$	0.48

Charles River management believes that supplementary non-GAAP financial measures provide useful information to allow investors to gain a meaningful understanding of our core operating results and future prospects, without the effect of one-time charges, consistent with the manner in which management measures and forecasts the Company’s performance. The supplementary non-GAAP financial measures included are not meant to be considered superior to, or a substitute for results of operations prepared in accordance with GAAP. The Company intends to continue to assess the potential value of reporting non-GAAP results consistent with applicable rules and regulations.

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