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Leasehold Improvements and Equipment (Tables)
9 Months Ended
Sep. 30, 2019
Notes to Financial Statements [Abstract]  
Schedule of Leasehold Improvements and Equipment [Table Text Block]
         September 30,  December 31, 
         2019   2018 
      Accumulated  Net Carrying   Net Carrying 
   Cost  Depreciation  Amount   Amount 
 Manufacturing equipment$ 4,471 $ 789 $ 3,682  $ 3,512 
 Laboratory and office equipment 1,327  822  505   562 
 Computer equipment 123  78  45   39 
 Leasehold improvements 3,244  1,166  2,078   2,135 
  $ 9,165 $ 2,855 $ 6,310  $ 6,248