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Revenue and Segment Information - Narrative (Details)
$ in Millions
12 Months Ended
Dec. 31, 2021
USD ($)
segment
Dec. 31, 2020
USD ($)
Dec. 31, 2019
USD ($)
Segment Reporting Information [Line Items]      
Revenue $ 6,739.8 $ 5,255.0 $ 5,517.9
Number of operating segments | segment 3    
Number of reportable segments | segment 3    
One Customer | Revenue from Contract with Customer Benchmark | Customer Concentration Risk      
Segment Reporting Information [Line Items]      
Concentration risk, percentage 13.00% 11.00%  
Product      
Segment Reporting Information [Line Items]      
Revenue $ 6,719.9 $ 5,227.8 5,492.0
Product development agreements      
Segment Reporting Information [Line Items]      
Revenue 19.9 $ 27.2 $ 25.9
Long Term Supply Arrangement      
Segment Reporting Information [Line Items]      
Contract liability 57.1    
Contract receivable 11.5    
Current contract liability 25.8    
Noncurrent contract liability $ 30.0