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Balance Sheet Components (Tables)
12 Months Ended
Dec. 31, 2017
Balance Sheet Related Disclosures [Abstract]  
Schedule of Inventories
Inventories consist of the following (in thousands): 
 
December 31,
 
2017
 
2016
Raw materials
$
12,721

 
$
9,793

Work in process
12,157

 
10,773

Finished goods
6,810

 
6,565

Total inventories
$
31,688

 
$
27,131

Property, Plant and Equipment
Property, plant and equipment consist of the following (in thousands):
 
 
 
December 31,
 
Generally Used Estimated Useful Life
 
2017
 
2016
Clinical and manufacturing equipment
Up to 10 years
 
$
183,392

 
$
153,938

Computer hardware
3 years
 
24,933

 
27,978

Computer software
3 years
 
54,756

 
59,997

Furniture and fixtures
5 years
 
16,271

 
10,306

Leasehold improvements
Lease term (1)
 
37,756

 
22,370

Building
20 years
 
63,887

 
7,272

Land
 
17,630

 
3,072

CIP
 
85,976

 
25,948

Total
 
 
484,601

 
310,881

Less: Accumulated depreciation and amortization and impairment charges
 
 
(135,808
)
 
(135,714
)
Total property, plant and equipment, net
 
 
$
348,793

 
$
175,167



(1) Shorter of remaining lease term or estimated useful lives of asset

Schedule of Accrued Liabilities
Accrued liabilities consist of the following (in thousands): 
 
December 31,
 
2017
 
2016
Accrued payroll and benefits
$
103,004

 
$
79,214

Accrued expenses
27,318

 
21,811

Accrued income taxes
12,405

 
4,210

Accrued sales rebate
11,209

 
10,342

Accrued professional fees
6,316

 
3,604

Accrued warranty
5,929

 
3,841

Accrued sales tax and value added tax
5,503

 
5,032

Other accrued liabilities
22,514

 
6,278

Total accrued liabilities
$
194,198

 
$
134,332

Warranty accrual
Accrued warranty as of December 31, 2017 and 2016 consists of the following activity (in thousands):
 
Accrued warranty as of December 31, 2015
$
2,638

Charged to cost of net revenues
4,894

Actual warranty expenditures
(3,691
)
Accrued warranty as of December 31, 2016
3,841

Charged to cost of net revenues
7,195

Actual warranty expenditures
(5,107
)
Accrued warranty as of December 31, 2017
$
5,929