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Note 3 - Stockholders' Equity (Tables)
12 Months Ended
Dec. 31, 2017
Stock Options And Warrants Tables  
Summary of the warrant activity
   Number of Warrants  Weighted Average Exercise Price
Outstanding, December 31, 2015:   41,752   $375.00 
Granted   17,005    135.00 
Forfeited   (1,173)   375.00 
Exercised   (42,034)   375.00 
Outstanding at December 31, 2016:   15,550   $135.00 
Granted   486,351    15.00 
Forfeited   (339,932)     
Exercised   (501,901)   15.00 
Outstanding at December 31, 2016   —     $—   
           
Exercisable warrants:          
December 31, 2017   —     $—   
December 31, 2016   41,752   $375.00 
Summary of the stock option activity
   Number of Options  Weighted Average Exercise Price
Outstanding, December 31, 2015   1,249   $1,464.00 
Granted   —      —   
Exercised   —      —   
Expired   (3)   16,881.00 
Outstanding, December 31, 2016   1,246   $1,428.00 
Granted   —      —   
Exercised   —      —   
Expired   —      —   
Outstanding, December 31, 2017   1,246   $1,428.00 
           
Exercisable Options:          
December 31, 2016   1,246   $1,428.00 
December 31, 2017   1,246   $1,428.00 
Summary of outstanding and exercisable stock options
      Outstanding Options    Exercisable Options 
 

Range of

Exercise Prices

    

Number of

Options

    Weighted-Average Remaining Contractual Life    

Weighted-Average

Exercise Price

    

Number of

Options

    

Weighted-Average

Exercise Price

 
 $750.00 to $2,225.00    1,246    1.38   $1,428.73    1,246   $1428.73