CONSOLIDATED STATEMENTS OF STOCKHOLDERS' EQUITY - USD ($)	Common Stock At the Market Offering and LincoIn Park Agreements	Common Stock	Additional Paid- in Capital At the Market Offering and LincoIn Park Agreements	Additional Paid- in Capital	Accumulated Deficit	At the Market Offering and LincoIn Park Agreements	Total
Beginning Balance at Dec. 31, 2021		$ 8,308		$ 442,095,642	$ (398,118,355)		$ 43,985,595
Beginning Balance, Shares at Dec. 31, 2021		8,307,868
Issuance of common stock for cash		$ 61		202,069			202,130
Issuance of common stock for cash (in shares)		60,651
Stock-based compensation		$ 37		5,343,969			5,344,006
Stock-based compensation (in shares)		37,252
Net loss					(29,930,694)		(29,930,694)
Ending Balance at Dec. 31, 2022		$ 8,406		447,641,680	(428,049,049)		19,601,037
Ending Balance, Shares at Dec. 31, 2022		8,405,771
Issuance of common stock for cash	$ 277	$ 180	$ 1,014,363	(180)		$ 1,014,640
Issuance of common stock for cash (in shares)	277,834	180,410
Issuance of common stock from exercise of stock options		$ 28		90,450			$ 90,478
Issuance of common stock from exercise of stock options (in shares)		27,518					27,518
Stock-based compensation				1,583,202			$ 1,583,202
Net loss					(8,236,814)		(8,236,814)
Fractional shares adjustment due to reverse split		(113)
Ending Balance at Dec. 31, 2023		$ 8,891		$ 450,329,515	$ (436,285,863)		$ 14,052,543
Ending Balance, Shares at Dec. 31, 2023		8,891,420