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Income Taxes - Effective Income Tax Rate Reconciliation (Details)
12 Months Ended
Dec. 31, 2016
Dec. 31, 2015
Dec. 31, 2014
Effective income tax rate reconciliation      
U.S. Federal statutory tax rate (35.00%) (35.00%) (35.00%)
Deferred state taxes, net of federal benefit (3.10%) (3.10%) (1.20%)
Common stock warrant liability (2.60%) (2.30%) 20.60%
Other, net (1.60%) 0.30% 0.70%
Foreign provision to return adjustment (2.90%)    
Change in unrecognized tax benefits (0.70%)   (0.90%)
Change in valuation allowance 45.20% 40.10% 15.40%
Total effective income tax rate (0.70%) 0.00% (0.40%)