Consolidated Statements of Stockholders' Equity (Deficit) (USD $)	0 Months Ended					12 Months Ended
	Apr. 30, 2014	Mar. 11, 2014	Jan. 15, 2014	Sep. 16, 2013	Feb. 20, 2013	Dec. 31, 2014		Dec. 31, 2013		Dec. 31, 2012	Dec. 31, 2011
Increase (Decrease) in Stockholders' Equity
Balance						$ (17,872,150)		$ 15,030,303		$ 29,035,665
Balance (in shares)						106,356,558
Net loss attributable to the Company						(88,487,823)		(62,669,682)		(31,862,454)
Other Comprehensive Income (Loss), Net of Tax, Total								(106,605)		75,668
Stock based compensation						4,052,761		2,149,492		1,991,154
Public offering, common stock, net						153,949,378	[1]	10,422,424	[2]	15,790,270
Public offering, common stock, net (in shares)	22,600,000	3,902,440	10,000,000	18,600,000	18,910,000
Exercise of warrants						101,785,107	[3]	17,301,918	[4]
Exercise of warrants (in shares)						23,832,038
Shares issued for acquisition						4,000,000
Conversion of preferred stock						1,218,360
Stock option exercises						(362,514)
Balance						158,283,119		(17,872,150)		15,030,303
Balance (in shares)						173,644,532		106,356,558
Common Stock
Increase (Decrease) in Stockholders' Equity
Balance						1,063,566		384,048		229,244
Balance (in shares)						106,356,558		38,404,764		22,924,411
Stock based compensation						1,462		21,982		5,304
Stock based compensation (in shares)						146,174		2,198,154		530,353
Public offering, common stock, net						365,024	[1]	431,018	[2]	149,500
Public offering, common stock, net (in shares)						36,502,440	[1]	43,101,800	[2]	14,950,000
Exercise of warrants						239,184	[3]	224,950	[4]
Exercise of warrants (in shares)						23,918,429	[3]	22,494,987	[4]
Stock dividend						342		1,568
Stock dividend (in shares)						34,232		156,853
Shares issued for acquisition						5,305
Shares issued for acquisition						530,504
Conversion of preferred stock						55,217
Shares issued upon conversion of redeemable stock (in shares)						5,521,676
Stock option exercises						6,345
Stock option exercises (in shares)						634,519
Balance						1,736,445		1,063,566		384,048
Balance (in shares)						173,644,532		106,356,558		38,404,764
Additional Paid-in-Capital
Increase (Decrease) in Stockholders' Equity
Balance						831,155,925		801,840,491		784,213,871
Stock based compensation						4,051,299		2,127,510		1,985,850
Public offering, common stock, net						153,584,354	[1]	9,991,406	[2]	15,640,770
Exercise of warrants						101,886,304	[3]	17,076,968	[4]
Stock dividend						155,535		119,550
Shares issued for acquisition						3,994,695
Conversion of preferred stock						1,163,143
Stock option exercises						400,413
Balance						1,096,391,668		831,155,925		801,840,491
Accumulated Other Comprehensive Income
Increase (Decrease) in Stockholders' Equity
Balance								1,004,412		928,744
Other Comprehensive Income (Loss), Net of Tax, Total								(106,605)		75,668
Balance						897,807		897,807		1,004,412
Treasury Stock
Increase (Decrease) in Stockholders' Equity
Balance						(1,552,382)					(1,552,382)
Balance (in shares)						165,906					165,906
Exercise of warrants						(340,381)	[3]
Exercise of warrants (in shares)						86,391	[3]
Stock option exercises						(769,272)
Stock option exercises (in shares)						125,819
Balance						(2,662,035)				(1,552,382)	(1,552,382)
Balance (in shares)						378,116				165,906	165,906
Accumulated Deficit
Increase (Decrease) in Stockholders' Equity
Balance						(849,437,066)		(786,646,266)		(754,783,812)
Net loss attributable to the Company						(88,487,823)		(62,669,682)		(31,862,454)
Stock dividend						(155,877)		(121,118)
Balance						$ (938,080,766)		$ (849,437,066)		$ (786,646,266)

[1] As a result of the January, March and April 2014 public offerings discussed in Note 5, Stockholders’ Equity, the Company received net proceeds of $165,722,618 of which $11,773,240 in value was ascribed to the warrants issued in the January 2014 public offering. The associated warrants have been separately valued and classified as a liability on the accompanying consolidated balance sheet.

[2] As a result of the 2013 public offerings discussed in Note 5, Stockholders’ Equity, the Company received net proceeds of $12,873,452, of which $2,451,028 in value was ascribed to the warrants issued in the February 2013 public offering.

[3] Pursuant to the exercise of warrants, additional paid-in capital was increased by $18,441,730 from the issuance of 23,832,038 shares of common stock. Additionally, paid-in capital was increased by $83,444,574 and warrant liability was reduced by $83,444,574 (the fair value of the warrants on the exercise date).

[4] Pursuant to the exercise of warrants, additional paid-in capital was increased by $5,878,146 from the issuance of 22,494,987 shares of common stock. Additionally, paid-in capital was increased by $11,198,822 and warrant liability was reduced by $11,198,822 (the fair value of the warrants on the exercise date).