Condensed Consolidated Statements of Operations (USD $)	3 Months Ended		9 Months Ended
	Sep. 30, 2011	Sep. 30, 2010	Sep. 30, 2011	Sep. 30, 2010
Income Statement [Abstract]
Product and service revenue	$ 4,312,885	$ 4,795,534	$ 11,927,135	$ 10,284,480
Research and development contract revenue	994,244	957,270	3,342,187	2,943,261
Licensed technology revenue	163,125		489,375
Total revenue	5,470,254	5,752,804	15,758,697	13,227,741
Cost of product and service revenue	7,565,994	7,344,444	19,187,617	15,174,670
Cost of research and development contract revenue	1,695,171	1,729,962	5,505,767	5,290,848
Research and development expense	1,478,847	2,085,622	3,647,821	11,954,153
Selling, general and administrative expenses	3,606,505	3,430,197	11,051,020	17,828,728
Gain on sale of leased assets	(673,358)		(673,358)
Amortization of intangible assets	584,606	562,785	1,754,568	1,691,840
Operating loss	(8,787,511)	(9,400,206)	(24,714,738)	(38,712,498)
Interest and other income and net realized losses from available-for-sale securities	99,740	141,930	220,862	752,591
Change in fair value of common stock warrant liability	2,414,267		4,204,787
Change in fair value of auction rate securities repurchase agreement		(2,842,790)		(5,977,822)
Net trading gain		2,842,790		5,977,822
Interest and other expense and foreign currency gain (loss)	(17,042)	(33,289)	2,675	(406,363)
Net loss	$ (6,290,546)	$ (9,291,565)	$ (20,286,414)	$ (38,366,270)
Loss per share:
Basic and diluted (in dollars per share)	$ (0.28)	$ (0.71)	$ (1.16)	$ (2.93)
Weighted average number of common shares outstanding (in shares)	22,676,114	13,150,113	17,441,767	13,103,837