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EQUITY INCENTIVE PLAN, Summary (Details) - USD ($)
3 Months Ended 6 Months Ended 12 Months Ended
Jun. 25, 2021
Jun. 30, 2022
Mar. 31, 2022
Jun. 30, 2021
Jun. 30, 2022
Jun. 30, 2021
Dec. 31, 2021
Jun. 18, 2019
Jun. 19, 2014
Stock Compensation Expense [Abstract]                  
Allocated share-based compensation expense   $ 559,009   $ 585,844 $ 1,309,912 $ 1,165,632      
Stock Options, Additional Disclosure [Abstract]                  
Outstanding, aggregate intrinsic value, end of period   0     0        
Exercisable, aggregate intrinsic value, end of period   0     0        
Cost of Product Sales [Member]                  
Stock Compensation Expense [Abstract]                  
Allocated share-based compensation expense   57,096   43,368 111,346 72,136      
Research and Development Expenses [Member]                  
Stock Compensation Expense [Abstract]                  
Allocated share-based compensation expense   112,318   139,469 203,507 223,704      
Selling, General and Administrative Expenses [Member]                  
Stock Compensation Expense [Abstract]                  
Allocated share-based compensation expense   $ 389,595   $ 403,007 $ 995,059 $ 869,792      
Stock Options [Member]                  
Assumptions Made in Calculating Fair Values of Options [Abstract]                  
Expected term   5 years 6 months     6 years        
Expected volatility   95.80%     91.62%        
Expected dividend yield              
Risk-free interest rate   3.09%     1.97%        
Stock Options, Number of Shares [Roll forward]                  
Outstanding, beginning of period (in shares)     1,600,372   1,600,372        
Granted (in shares)         2,481,968        
Exercised (in shares)         0        
Forfeited (in shares)         121,159        
Expired (in shares)         184,745        
Outstanding, end of period (in shares)   3,776,436     3,776,436   1,600,372    
Exercisable, end of period (in shares)   636,924     636,924        
Stock Options, Weighted Average Exercise Price per Share [Roll Forward]                  
Outstanding, beginning of period (in dollars per share)     $ 4.18   $ 4.18        
Granted (in dollars per share)         1.24        
Exercised (in dollars per share)         0        
Forfeited (in dollars per share)         2.93        
Expired (in dollars per share)         5.63        
Outstanding, end of period (in dollars per share)   $ 2.21     2.21   $ 4.18    
Exercisable, end of period (in dollars per share)   $ 0     $ 0        
Stock Options, Additional Disclosure [Abstract]                  
Outstanding, weighted average remaining contract term         8 years 4 months 13 days   6 years 7 months 2 days    
Exercisable, weighted average remaining contract term         5 years 29 days        
Outstanding, aggregate intrinsic value, beginning of period     $ 0   $ 0        
Granted, aggregate intrinsic value         0        
Exercised, aggregate intrinsic value         0        
Forfeited, aggregate intrinsic value         0        
Outstanding, aggregate intrinsic value, end of period   $ 0     0   $ 0    
Exercisable, aggregate intrinsic value, end of period   $ 0     $ 0        
2014 Stock Incentive Plan [Member] | Stock Options [Member]                  
Share-based Arrangements with Employees and Nonemployees [Abstract]                  
Number of shares authorized under the plan (in shares)                 800,000
Number of stock options expired, forfeited or exercised under the plan (in shares)     732,064            
Options still available to be issued (in shares)   0     0        
Stock Options, Number of Shares [Roll forward]                  
Outstanding, end of period (in shares)   46,875     46,875        
2019 Omnibus Incentive Plan [Member] | Stock Options [Member]                  
Share-based Arrangements with Employees and Nonemployees [Abstract]                  
Number of shares authorized under the plan (in shares) 4,800,000             2,400,000  
Increase in number of shares authorized (in shares) 2,400,000                
Number of stock options expired, forfeited or exercised under the plan (in shares)         1,048,966        
Options still available to be issued (in shares)   35,629     35,629        
Stock Options, Number of Shares [Roll forward]                  
Outstanding, end of period (in shares)   4,950,291     4,950,291        
2014 & 2019 Stock Incentive Plan [Member] | Stock Options [Member]                  
Stock Options, Number of Shares [Roll forward]                  
Outstanding, end of period (in shares)   21,061     21,061