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EQUITY INCENTIVE PLAN, Summary (Details) - USD ($)
3 Months Ended 12 Months Ended
Jun. 25, 2021
Mar. 31, 2022
Mar. 31, 2021
Dec. 31, 2021
Jun. 18, 2019
Jun. 19, 2014
Stock Compensation Expense [Abstract]            
Allocated share-based compensation expense   $ 750,903 $ 579,789      
Stock Options, Additional Disclosure [Abstract]            
Outstanding, aggregate intrinsic value, end of period   0        
Exercisable, aggregate intrinsic value, end of period   0        
Cost of Product Sales [Member]            
Stock Compensation Expense [Abstract]            
Allocated share-based compensation expense   54,250 28,768      
Research and Development Expenses [Member]            
Stock Compensation Expense [Abstract]            
Allocated share-based compensation expense   91,189 90,920      
Selling, General and Administrative Expenses [Member]            
Stock Compensation Expense [Abstract]            
Allocated share-based compensation expense   $ 605,464 $ 460,101      
Stock Options [Member]            
Assumptions Made in Calculating Fair Values of Options [Abstract]            
Expected term   6 years        
Expected volatility   91.40%        
Expected dividend yield          
Risk-free interest rate   1.91%        
Stock Options, Number of Shares [Roll forward]            
Outstanding, beginning of period (in shares)   1,600,372        
Granted (in shares)   2,358,539        
Exercised (in shares)   0        
Forfeited (in shares)   14,883        
Expired (in shares)   183,241        
Outstanding, end of period (in shares)   3,760,787   1,600,372    
Exercisable, end of period (in shares)   565,215        
Stock Options, Weighted Average Exercise Price per Share [Roll Forward]            
Outstanding, beginning of period (in dollars per share)   $ 4.18        
Granted (in dollars per share)   1.23        
Exercised (in dollars per share)   0        
Forfeited (in dollars per share)   2.42        
Expired (in dollars per share)   5.63        
Outstanding, end of period (in dollars per share)   2.27   $ 4.18    
Exercisable, end of period (in dollars per share)   $ 3.68        
Stock Options, Additional Disclosure [Abstract]            
Outstanding, weighted average remaining contract term   8 years 7 months 24 days   6 years 7 months 2 days    
Exercisable, weighted average remaining contract term   5 years 10 months 20 days        
Outstanding, aggregate intrinsic value, beginning of period   $ 0        
Granted, aggregate intrinsic value   0        
Exercised, aggregate intrinsic value   0        
Forfeited, aggregate intrinsic value   0        
Outstanding, aggregate intrinsic value, end of period   0   $ 0    
Exercisable, aggregate intrinsic value, end of period   $ 0        
2014 Stock Incentive Plan [Member] | Stock Options [Member]            
Share-based Arrangements with Employees and Nonemployees [Abstract]            
Number of shares authorized under the plan (in shares)           800,000
Number of stock options expired, forfeited or exercised under the plan (in shares)   732,064        
Options still available to be issued (in shares)   0        
Stock Options, Number of Shares [Roll forward]            
Outstanding, end of period (in shares)   46,875        
2019 Omnibus Incentive Plan [Member] | Stock Options [Member]            
Share-based Arrangements with Employees and Nonemployees [Abstract]            
Number of shares authorized under the plan (in shares) 4,800,000       2,400,000  
Increase in number of shares authorized (in shares) 2,400,000          
Number of stock options expired, forfeited or exercised under the plan (in shares)   866,709        
Options still available to be issued (in shares)   83,234        
Stock Options, Number of Shares [Roll forward]            
Outstanding, end of period (in shares)   4,915,279        
2014 & 2019 Stock Incentive Plan [Member] | Stock Options [Member]            
Stock Options, Number of Shares [Roll forward]            
Outstanding, end of period (in shares)   21,061