Termination Benefits and Other Cost Reduction Actions - Additional Information (Detail) - USD ($) $ in Thousands	3 Months Ended
	Mar. 31, 2016	Mar. 31, 2015
Restructuring Cost And Reserve [Line Items]
Restructuring costs	$ 4,130	$ 2,755
Non cash portion of net costs related to abandoned assets	200
Clinical [Member]
Restructuring Cost And Reserve [Line Items]
Restructuring costs	1,200	1,000
Commercial [Member]
Restructuring Cost And Reserve [Line Items]
Restructuring costs	2,900	1,700
Corporate [Member]
Restructuring Cost And Reserve [Line Items]
Restructuring costs		100
Cost of Revenues [Member]
Restructuring Cost And Reserve [Line Items]
Restructuring costs	1,500	1,300
SG&A Expenses [Member]
Restructuring Cost And Reserve [Line Items]
Restructuring costs	$ 2,600	$ 1,400