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STATEMENTS OF CASH FLOWS (USD $)
In Thousands, unless otherwise specified
12 Months Ended
Dec. 31, 2012
Dec. 31, 2011
Dec. 31, 2010
Operating activities      
Net loss $ (38,048) $ (32,354) $ (25,966)
Adjustments to reconcile net loss to net cash used in operations:      
Stock-based compensation 5,310 3,435 2,116
Accretion of interest expense 1,680    
Amortization of debt financing costs 17    
Depreciation and amortization of property and equipment 27 3 6
Changes in operating assets and liabilities:      
Trade receivables (557)    
Inventory (4,663)    
Prepaid expenses and other current assets (480) 278 135
Other assets 11 72 (23)
Accounts payable 193 2,794 (453)
Accrued clinical expenses 199 (171) 106
Accrued compensation and other liabilities 275 (1,457) 1,794
Deferred revenue 16    
Net cash used in operating activities (36,020) (27,400) (22,285)
Investing activities      
Purchases of property and equipment (151) (25)  
Net cash used in investing activities (151) (25)  
Financing activities      
Proceeds from issuance of common stock and warrants, including collection of stockholder notes receivable, net of cash paid for issuance costs 59,708 42,482 23,002
Proceeds from issuance of long-term obligation, net of cash paid for issuance costs 29,860    
Principal payments of obligations under capital leases     (6)
Net cash provided by financing activities 89,568 42,482 22,996
Net increase in cash and cash equivalents 53,397 15,057 711
Cash and cash equivalents at beginning of period 39,635 24,578 23,867
Cash and cash equivalents at end of period $ 93,032 $ 39,635 $ 24,578