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Stockholders' Equity (Details)
3 Months Ended
Mar. 31, 2019
USD ($)
$ / shares
shares
Stockholders' Equity Note [Abstract]  
Stock options outstanding, beginning | shares 302,772
Stock options granted | shares 99,072
Stock options forfeited | shares (20,432)
Stock options outstanding, ending | shares 381,412
Weighted average exercise price outstanding, beginning | $ / shares $ 18.30
Weighted average exercise price granted | $ / shares 2.32
Weighted average exercise price forfeited | $ / shares 13.20
Weighted average exercise price outstanding, ending | $ / shares $ 14.41
Weighted average remaining contractual life, beginning 7 years 2 months 12 days
Weighted average remaining contractual life granted 9 years 10 months 2 days
Weighted average remaining contractual life, ending 7 years 7 months 6 days
Aggregate intrinsic value outstanding, beginning | $ $ 0
Aggregate intrinsic value granted | $ 63,802
Aggregate intrinsic value forfeited | $ 0
Aggregate intrinsic value outstanding, ending | $ $ 241,597