Summary of Significant Accounting Policies (Details 1) - shares	3 Months Ended
	Mar. 31, 2019	Mar. 31, 2018
Antidilutive securities excluded from computation of earnings per share	3,239,776	3,813,796
Common Stock Options [Member]
Antidilutive securities excluded from computation of earnings per share	381,412	171,442
Series A, H-1, H-3, H-4, I, J and Merger Common Stock Purchase Warrants
Antidilutive securities excluded from computation of earnings per share	585,306	658,486
Series H, H-3, and H-4 Convertible Preferred Stock [Member]
Antidilutive securities excluded from computation of earnings per share	2,028,415	2,739,225
Restricted Shares (Unvested) [Member]
Antidilutive securities excluded from computation of earnings per share	244,643	244,643