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Income Taxes - Schedule of NOL Carryforwards (Details) - USD ($)
$ in Thousands
Dec. 31, 2020
Dec. 31, 2019
Operating Loss Carryforwards [Line Items]    
Federal and state research and development tax credit and other credit carryforwards $ 132,800 $ 88,570
Domestic country    
Operating Loss Carryforwards [Line Items]    
NOL carryforwards: 59,200 87,500
State and local jurisdiction    
Operating Loss Carryforwards [Line Items]    
NOL carryforwards: 24,800 20,500
Foreign country    
Operating Loss Carryforwards [Line Items]    
NOL carryforwards: $ 40,800 $ 11,600