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Share-Based Compensation - Share Tracking Awards Plans - Benefit recognized (Details) - USD ($)
$ in Millions
3 Months Ended 9 Months Ended
Sep. 30, 2019
Sep. 30, 2018
Sep. 30, 2019
Sep. 30, 2018
Share based compensation benefit recognized in connection with the STAP        
Share-based compensation expense (benefit) before tax $ 23.9 $ 51.4 $ 15.9 $ (29.2)
STAP awards        
Share based compensation benefit recognized in connection with the STAP        
Share-based compensation expense (benefit) before tax 1.4 32.2 (47.0) (80.1)
Related income tax (benefit) expense (0.2) (7.4) 10.7 18.3
Share-based compensation expense (benefit), net of taxes 1.2 24.8 (36.3) (61.8)
Cash payments on awards exercised during the period     6.9 71.5
Cost of product sales | STAP awards        
Share based compensation benefit recognized in connection with the STAP        
Share-based compensation expense (benefit) before tax 0.1 2.0 (1.9) (4.0)
Research and development | STAP awards        
Share based compensation benefit recognized in connection with the STAP        
Share-based compensation expense (benefit) before tax 0.4 6.8 (9.9) (15.2)
Selling, general and administrative | STAP awards        
Share based compensation benefit recognized in connection with the STAP        
Share-based compensation expense (benefit) before tax $ 0.9 $ 23.4 $ (35.2) $ (60.9)