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Share-Based Compensation - Stock and Status (Details) - Stock Options - USD ($)
$ / shares in Units, $ in Millions
3 Months Ended 9 Months Ended
Sep. 30, 2018
Sep. 30, 2019
Sep. 30, 2018
Options      
Outstanding at beginning of period (in shares)   6,299,803  
Granted (in shares)   2,081,047  
Exercised (in shares) (4,857) (191,508) (287,760)
Forfeited/canceled (in shares)   (95,016)  
Outstanding at the end of period (in shares)   8,094,326  
Exercisable at the end of period (in shares)   3,915,462  
Unvested at the end of period (in shares)   4,178,864  
Weighted-Average Exercise Price      
Outstanding at beginning of period (in dollars per share)   $ 120.78  
Granted (in dollars per share)   124.87  
Exercised (in dollars per share)   51.53  
Forfeited (in dollars per share)   131.04  
Outstanding at the end of period (in dollars per share)   123.35  
Exercisable at the end of period (in dollars per share)   119.40  
Unvested at the end of period (in dollars per share)   $ 127.05  
Weighted Average Remaining Contractual Term (in Years)      
Outstanding at the end of period (in Years)   6 years 6 months  
Exercisable at the end of period (in Years)   5 years 4 months 24 days  
Unvested at the end of period (in Years)   7 years 7 months 6 days  
Outstanding at the end of period)   $ 8.4  
Exercisable at the end of period   8.2  
Unvested at the end of period   $ 0.2  
Share-based Compensation Arrangement by Share-based Payment Award, Options, Aggregate Intrinsic Value Disclosures [Abstract]      
Weighted average grant date fair value of stock options (in dollars per share)   $ 39.63 $ 45.02
Aggregate grant date fair value   $ 82.5 $ 44.3
Total grant date fair value of employee stock options that vested   $ 36.4 $ 33.9