Share Tracking Awards Plans - Expense Recognized (Details) - Share tracking award plans (STAP) - USD ($) $ in Millions	3 Months Ended	9 Months Ended
Sep. 30, 2017	Sep. 30, 2016	Sep. 30, 2017	Sep. 30, 2016
Share based compensation benefit recognized in connection with the STAP
Share-based compensation benefit before taxes	$ (38.0)	$ 45.8	$ (77.5)	$ (116.5)
Related income tax expense	13.9	(17.1)	28.4	42.6
Share-based compensation benefit, net of taxes	(24.1)	28.7	(49.1)	(73.9)
Cash payments on awards exercised during the period			54.1	52.7
Cost of product sales
Share based compensation benefit recognized in connection with the STAP
Share-based compensation benefit before taxes	(2.1)	3.5	(4.7)	(8.7)
Research and development
Share based compensation benefit recognized in connection with the STAP
Share-based compensation benefit before taxes	(8.2)	8.1	(16.9)	(31.6)
Selling, general and administrative
Share based compensation benefit recognized in connection with the STAP
Share-based compensation benefit before taxes	$ (27.7)	$ 34.2	$ (55.9)	$ (76.2)

Represents the expense recognized during the period arising from equity-based compensation arrangements (for example, shares of stock, unit, stock options or other equity instruments) with employees, directors and certain consultants qualifying for treatment as employees.

Reference 1: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 718
-SubTopic 10
-Section S99
-Paragraph 1
-Subparagraph (SAB Topic 14.F)
-URI http://asc.fasb.org/extlink&oid=27013229&loc=d3e301413-122809

Reference 2: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 718
-SubTopic 10
-Section 50
-Paragraph 1
-Subparagraph (b)
-URI http://asc.fasb.org/extlink&oid=6415400&loc=d3e5047-113901

Reference 3: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 718
-SubTopic 10
-Section 50
-Paragraph 2
-Subparagraph (h)(1)(i)
-URI http://asc.fasb.org/extlink&oid=6415400&loc=d3e5070-113901

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The amount of expense, net of income tax, recognized during the period arising from equity-based compensation arrangements (for example, shares of stock, unit, stock options or other equity instruments) with employees, directors and certain consultants qualifying for treatment as employees.

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- Definition

Aggregate cash paid by the entity during the period to settle equity instruments granted under equity-based payment arrangements.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 718
-SubTopic 10
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-URI http://asc.fasb.org/extlink&oid=6415400&loc=d3e5070-113901

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- Definition

The total recognized tax benefit related to compensation cost for equity-based payment arrangements recognized in income during the period.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 718
-SubTopic 10
-Section 50
-Paragraph 2
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-URI http://asc.fasb.org/extlink&oid=6415400&loc=d3e5070-113901

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